ACTION OF THE ANTIBIOTICS OF THE ITURIN GROUP ON ARTIFICIAL MEMBRANES

ACTION OF THE ANTIBIOTICS OF THE ITURIN GROUP ON ARTIFICIAL MEMBRANES
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DOI:
10.7164/antibiotics.37.646
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发表时间:
1984-01-01
影响因子:
3.3
通讯作者:
MICHEL, G
MICHEL, G
中科院分区:
医学4区
文献类型:
--
作者:
BESSON, F;MICHEL, G

文献摘要

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研究了伊枯草菌素 A 和芽孢杆菌素 L 对二棕榈酰磷脂酰胆碱 (DPPC) 和 DPPC-胆固醇囊泡的作用。 Iturin A 破坏了囊泡; bacillomycin L 与 DPPC 囊泡结合并破坏含有 DPPC 和胆固醇的囊泡。将这些结果与伊枯草菌群抗生素对细胞质膜的作用进行比较进行讨论。
The action of iturin A and bacillomycin L on vesicles of dipalmitoylphosphatidylcholine (DPPC) and DPPC-cholesterol was studied. Iturin A destroyed the vesicles; bacillomycin L bound with DPPC vesicles and destroyed vesicles containing DPPC and cholesterol. These results are discussed in comparison with the action of antibiotics of the iturin group on cytoplasmic membranes.