Reassessing the cardiac risk profile in chronic hemodialysis patients: a hypothesis on the role of oxidant stress and other non-traditional cardiac risk factors.

Reassessing the cardiac risk profile in chronic hemodialysis patients: a hypothesis on the role of oxidant stress and other non-traditional cardiac risk factors.
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DOI:
10.1681/asn.v83475
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发表时间:
1997-03
期刊:
Journal of the American Society of Nephrology : JASN
影响因子:
--
通讯作者:
B. Becker;J. Himmelfarb;W. Henrich;R. Hakim
B. Becker;J. Himmelfarb;W. Henrich;R. Hakim
中科院分区:
其他
文献类型:
--
作者:
B. Becker;J. Himmelfarb;W. Henrich;R. Hakim

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心血管疾病是一般人群中最大的单一死亡原因(1),因此,它也是慢性血液透析患者死亡的主要原因并不奇怪,占美国该人群所有死亡的近一半(2)。许多研究描述了ESRD人群中动脉粥样硬化性心血管疾病(2,3)和充血性心力衰竭(4,5)的高患病率,这些疾病占慢性血液透析人群心血管死亡率的绝大多数。
Cardiovascular disease is the single largest cause of mortality in the general population (1) and, as such, it is not surprising that it is also the leading cause of mortality in chronic hemodialysis patients, accounting for nearly half of all deaths in this population in the United States (2). Numerous studies have described the high prevalence of atherosclerotic cardiovascular disease (2,3) and congestive heart failure in the ESRD population (4,5), with these entities accounting for a great majority of cardiovascular mortality in the chronic hemodialysis population.