Copper(I) Complexes Bearing Carbenes Beyond Classical N-Heterocyclic Carbenes: Synthesis and Catalytic Activity in "Click Chemistry"
Copper(I) Complexes Bearing Carbenes Beyond Classical N-Heterocyclic Carbenes: Synthesis and Catalytic Activity in "Click Chemistry"
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DOI：
10.1002/adsc.201500453
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发表时间：
2015-10-12
影响因子：
5.4
通讯作者：
Cazin, Catherine S. J.
中科院分区：
文献类型：
--
作者：
Bidal, Yannick D.;Lesieur, Mathieu;Cazin, Catherine S. J.
报道了反常N-杂环卡宾、环(烷基)(氨基)卡宾和介离子卡宾铜(I)配合物的合成和表征。这些有机金属物种是通过使用容易获得的反应物，即氧化铜和亚胺盐，通过一种多用途和廉价的合成途径获得的。考察了该系列络合物在[3+2]炔烃与叠氮化物的[3+2]环加成反应(CuAAC)中的催化活性。反常的NHC和三唑亚甲基铜(I)络合物具有优异的催化性能。
The synthesis and characterization of abnormal N-heterocyclic carbene, cyclic (alkyl)(amino)carbene, and mesoionic carbene copper(I) complexes are reported. These organometallic species are obtained via a versatile and inexpensive synthetic pathway using readily available reactants, namely copper oxide and iminium salts. The catalytic activity of this series of complexes was evaluated in the [3+2] cycloaddition of alkynes with azides (CuAAC). Outstanding catalytic properties were observed for the abnormal NHC- and triazolylidene-based copper(I) complexes.