Mild cognitive impairment. When is it a precursor to Alzheimer's disease?

Mild cognitive impairment. When is it a precursor to Alzheimer's disease?
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DOI:
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发表时间:
2000
期刊:
影响因子:
2.3
通讯作者:
Y. Shah;E. Tangalos;Ronald C. Petersen
Y. Shah;E. Tangalos;Ronald C. Petersen
中科院分区:
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文献类型:
--
作者:
Y. Shah;E. Tangalos;Ronald C. Petersen

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有很好的证据表明,阿尔茨海默病的发作通常是由一个过渡阶段称为轻度认知障碍(MCI)。经历这种情况的人患阿尔茨海默病的风险增加。诊断MCI包括排除其他疾病,并确定患者是否符合预定义的评估标准。没有预防MCI的治疗方法,但了解病情可以改善患者管理。一些临床试验正在进行中,以研究潜在的潜在MCI药物。
There is good evidence suggesting that onset of Alzheimer's disease is commonly preceded by an interim phase known as mild cognitive impairment (MCI). Persons who experience this condition are at increased risk for the development of Alzheimer's disease. Diagnosing MCI involves excluding other morbidities and determining whether the patient meets predefined assessment criteria. There is no treatment for the prevention of MCI, but an understanding of the condition can improve patient management. Several clinical trials are underway to investigate potential potential MCI agents.