Greater Cincinnati/Northern Kentucky Stroke Study - Volume of first-ever ischemic stroke among blacks in a population-based study
Greater Cincinnati/Northern Kentucky Stroke Study - Volume of first-ever ischemic stroke among blacks in a population-based study
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DOI：
10.1161/01.str.32.6.1285
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发表时间：
2001-06-01
期刊：
影响因子：
8.3
通讯作者：
Tomsick, T
中科院分区：
文献类型：
--
作者：
Kissela, B;Broderick, J;Tomsick, T
背景和目的-在急性卒中治疗试验中，以标准化的方式研究了CT扫描显示的缺血性卒中体积，中位体积为10.5 - 55 cm（3）。首次缺血性中风的人口中的体积是未知的。方法-第一阶段的人口为基础的大辛辛那提/北方肯塔基州中风研究确定了所有的缺血性中风发生在黑人在大辛辛那提地区之间的1993年1月至6月。在这一阶段的研究谁有一个首次缺血性临床中风的患者进行了鉴定，缺血性中风的体积measured.Results -有257验证缺血性中风的临床病例，其中181首次缺血性梗死。其中150名患者有影像学检查，79名患者在CT或MRI检查中有明确或可能与临床症状相关的梗死。对于这些患者，通过改良的椭球体方法进行体积测量。79例患者首次缺血性卒中的中位体积为2.5 cm（3）（四分位距，0.5 - 8.8 cm（3））。病变部位与梗死面积有显著相关性（P
Background and Purpose - The Volume of ischemic stroke on CT scans has been studied in a standardized fashion in acute stroke therapy trials with median volumes between 10.5 to 55 cm(3). The volume of first-ever ischemic stroke in the population is not known.Methods - The first phase of the population-based Greater Cincinnati/Northern Kentucky Stroke Study identified all ischemic strokes occurring in blacks in the greater Cincinnati region between January and June of 1993. The patients in this phase of the study who had a first-ever ischemic clinical stroke were identified, and the volume of ischemic stroke was measured.Results - There were 257 verified clinical cases of ischemic stroke, of which 181 had a first-ever ischemic infarct. imaging was available for 150 of these patients, and 79 had an infarct on the CT or MRI study that was definitely or possibly related to the clinical symptoms. For these patients, volumetric measurements were performed by means of the modified ellipsoid method. The median volume of first-ever ischemic stroke for the 79 patients was 2.5 cm(3) (interquartile range, 0.5 to 8.8 cm(3)). There was a significant relation between location of lesion and infarct size (P