Significance of raised immunoglobulin M levels in cord blood of small-for-gestational-age infants.
Significance of raised immunoglobulin M levels in cord blood of small-for-gestational-age infants.
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小于胎龄儿脐带血中免疫球蛋白 M 水平升高的意义。
DOI：
10.1136/adc.53.11.895
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发表时间：
1978
影响因子：
5.2
通讯作者：
C. O'Herlihy
中科院分区：
文献类型：
--
作者：
T. Matthews;C. O'Herlihy
脐带 IgM 值是在 Hammersmith 医院出生的 5 1/2 岁的小于胎龄婴儿中测定的。 121 名婴儿 (12.5%) 的浓度超过 0.2 克/升； 92 中的浓度在 0.21 至 0.3 克/升之间。只有 18 例 (14.8%) 的水平超过 0.4 克/升，并且有 5 例已证实宫内感染病例——风疹 (2 例)、梅毒 (2 例) 和弓形体病 (1 例)。与脐带 IgM 超过 0.4 g/l 最常见的因素是胎膜破裂时间延长。母亲中 B 型血的发生率有所增加，这可能反映了更多的非白人女性生下了小于胎龄儿。脐带IgM测定对诊断无明显帮助。
Cord IgM values were determined in small-for-gestational-age infants born at Hammersmith Hospital during a 5 1/2-year period. 121 (12.5%) infants had levels more than 0.2 g/l; in 92 these were between 0.21 and 0.3 g/l. In only 18 (14.8%) was a level of 0.4 g/l exceeded, and 5 proved cases of intrauterine infection--rubella (2), syphilis (2), and toxoplasmosis (1)--were in this group. The factor most often associated with cord IgM more than 0.4 g/l was prolonged rupture of the membranes. There was an increased incidence of blood group B among the mothers, probably reflecting the greater number of nonCaucasian women giving birth to small-for-gestational-age infants. Determination of cord IgM did not help significantly indiagnosis.