Higher Beck depression scores predict delayed epinephrine recovery after acute psychological stress independent of baseline levels of stress and mood
Higher Beck depression scores predict delayed epinephrine recovery after acute psychological stress independent of baseline levels of stress and mood
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DOI：
10.1016/j.biopsycho.2003.12.001
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发表时间：
2004-11-01
影响因子：
2.6
通讯作者：
Bovbjerg, DH
中科院分区：
文献类型：
--
作者：
Gold, SA;Zakowski, SG;Bovbjerg, DH
非临床范围内的抑郁症状与健康风险增加有关。最近的理论提出了一种可能性，即患有抑郁症状的个体对急性压力的生理反应增强和/或压力恢复减慢可能会导致风险增加。我们使用改良版的特里尔社会压力测试（15 分钟）对 52 名健康女性进行了研究，研究了压力引起的儿茶酚胺反应和恢复模式，并将贝克抑郁量表（BDI，中位数分割）中正常高分与低分的亚组与随机分配到无压力对照组的 29 名女性进行了比较。 BDI 高正常组和 BDI 低组在应激后立即表现出类似的肾上腺素急剧增加，但只有 BDI 高正常组在恢复期间仍显着高于对照组水平。去甲肾上腺素反应没有发现差异。 BDI 分数在正常范围内的升高可以选择性地预测急性应激后生理恢复较慢。 (C) 2004 Elsevier B.V. 保留所有权利。
Depressive symptoms in the non-clinical range have been linked to increased health risks. Recent theorizing raises the possibility that heightened physiologic responses to acute stress and/or slowed stress recovery in individuals with depressive symptoms may contribute to increased risk. We investigated stress-induced catecholamine responses and recovery patterns using a modified version of the Trier Social Stress Test (15 min) with a sample of 52 healthy women and compared subgroups with high normal versus low scores on the Beck Depression Inventory (BDI, median split) to 29 women randomly assigned to a non-stressed control group. The BDI-high normal and BDI-low groups showed similar acute increases in epinephrine immediately post stressor, but only the BDI-high normal group remained significantly elevated above control group levels during the recovery period. No differences were found in norepinephrine responses. Elevations in BDI scores within the normal range may selectively predict slower physiological recovery following acute stress. (C) 2004 Elsevier B.V. All rights reserved.