Cyclic AMP regulation of active chloride transport in the rectal gland of marine elasmobranchs.
Cyclic AMP regulation of active chloride transport in the rectal gland of marine elasmobranchs.
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DOI：
10.1002/jez.1401990319
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发表时间：
1977-03
期刊：
影响因子：
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通讯作者：
J. Stoff;P. Silva;M. Field;J. Forrest;A. Stevens;F. Epstein
中科院分区：
文献类型：
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作者：
J. Stoff;P. Silva;M. Field;J. Forrest;A. Stevens;F. Epstein
在体外灌流过程中，添加0.01~5 mM的茶碱或0.05 mM的二丁酰环AMP可显著促进角鱼直肠腺中氯离子的主动转运。效果发生得很快，可能会持续两个小时。具体的荷尔蒙效应器尚未确定。因此，分离的灌流直肠腺提供了一个独特的机会来研究活跃的氯化物分泌的细胞机制。
Active transport of chloride in the salt secreting rectal gland of the dogfish Squalus acanthias is markedly stimulated by the addition of theophylline (0.01 to 5 mM) or dibutyryl cyclic AMP (0.05 mM) during in vitro perfusion. The effect occurs promptly and may persist for two hours. Specific hormonal effectors have not yet been identified. The isolated perfused rectal gland thus offers a unique opportunity to examine the cellular mechanisms of active chloride secretion.