Viral suppression correlates with dendritic cell restoration in chronic hepatitis B patients with autologous cytokine‐induced killer cell transfusion
Viral suppression correlates with dendritic cell restoration in chronic hepatitis B patients with autologous cytokine‐induced killer cell transfusion
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DOI：
10.1111/j.1478-3231.2008.01861.x
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发表时间：
2009-03
影响因子：
6.7
通讯作者：
M. Shi;Jun‐liang Fu;F. Shi;Bin Zhang;Zi-rong Tang;Zheng Zhang;Hui Zhang;Lei Jin;Liming Chen-Liming
中科院分区：
文献类型：
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作者：
M. Shi;Jun‐liang Fu;F. Shi;Bin Zhang;Zi-rong Tang;Zheng Zhang;Hui Zhang;Lei Jin;Liming Chen-Liming
背景：慢性乙型肝炎 (CHB) 患者的髓系和浆细胞样树突状细胞 (mDC、pDC) 功能受损。过继性免疫疗法可以抑制慢性乙型肝炎患者的乙型肝炎病毒（HBV）复制，但是否可以恢复mDC和pDC的功能仍不清楚。
Background: Myeloid and plasmacytoid dendritic cells (mDCs, pDCs) are functionally impaired in patients with chronic hepatitis B (CHB). Adoptive immunotherapy can suppress hepatitis B virus (HBV) replication in CHB patients, but whether it can restore the functionality of mDCs and pDCs remains unknown.