Pancreatic Endoscopic Ultrasound-guided Fine Needle Aspiration: Complication rate and clinical course in a single centre
Pancreatic Endoscopic Ultrasound-guided Fine Needle Aspiration: Complication rate and clinical course in a single centre
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DOI：
10.1016/j.dld.2009.10.002
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发表时间：
2010-07-01
影响因子：
4.5
通讯作者：
Testoni, Pier Alberto
中科院分区：
文献类型：
--
作者：
Carrara, Silvia;Arcidiacono, Paolo Giorgio;Testoni, Pier Alberto
背景资料：内镜超声引导下细针抽吸术（EUS-FNA）是从胰腺病变中获得活检标本的有效方法。目的：确定单中心大型系列患者中胰腺实性和囊性病变EUS-FNA后并发症的频率和严重程度。患者和方法：从2005年1月到2008年12月，所有转诊到我们单位进行胰腺EUS的患者的信息系统地输入计算机数据库，包括临床和形态学数据。记录进行了审查，以评估是否并发症，如出血，急性胰腺炎，肠穿孔，或其他发生后EUS-FNA的pancreas.Results：共3296胰腺EUS在四年内完成。在1034例胰腺EUS-FNA中，我们观察到10例（0.96%）出血（7例囊内出血，2例胰管出血，1例小癌出血），2例（0.19%）急性重症胰腺炎和1例（0.09%）十二指肠穿孔，随后发生复杂的术后住院和死亡。出血都是自限性的。总体而言，主要并发症（胰腺炎和穿孔）出现在0.29%的这些examination.Conclusions：EUS-FNA是安全的，严重出血的风险低。虽然罕见，但急性胰腺炎通常是轻度或重度的，需要长期住院。一例十二指肠神经内分泌肿瘤和胰腺浸润患者在十二指肠穿孔后发生了致命性并发症。(C)2009 Editrice Gastroenterology Italiana S.r.l.由爱思唯尔有限公司出版。保留所有权利。
Background: Endoscopic Ultrasound-guided Fine Needle Aspiration (EUS-FNA) is effective for obtaining biopsy specimens from pancreatic lesions.Aim: To determine the frequency and severity of complications after EUS-FNA of solid and cystic pancreatic lesions in a single centre large series of patients.Patients and methods: From January 2005 to December 2008, information on all patients referred to our unit for pancreatic EUS was systematically entered in a computer database including clinical and morphologic data. Records were reviewed to evaluate whether complications such as haemorrhage, acute pancreatitis, intestinal perforation, or others occurred after EUS-FNA of the pancreas.Results: A total of 3296 pancreatic EUS were done in four years. In the 1034 pancreatic EUS-FNA, we observed 10 (0.96%) haemorrhages (7 intracystic, 2 in the pancreatic duct, and 1 in a small carcinoma), 2 (0.19%) acute severe pancreatitis and 1 (0.09%) duodenal perforation followed by complicated post-surgical hospitalization and death. The haemorrhages were all self-limiting. Overall, major complications (pancreatitis and perforation) arose in 0.29% of these examinations.Conclusions: EUS-FNA is safe, with a low risk of severe haemorrhage. Although rare, acute pancreatitis is generally mild or severe, requiring prolonged hospitalization. One fatal complication occurred after duodenal perforation in a patient with duodenal neuroendocrine tumour and pancreatic infiltration. (C) 2009 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.