Abnormalities of somatosensory perception in patients with painful osteoarthritis normalize following successful treatment
Abnormalities of somatosensory perception in patients with painful osteoarthritis normalize following successful treatment
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DOI：
10.1053/eujp.2000.0175
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发表时间：
2000-01-01
影响因子：
3.6
通讯作者：
Ordeberg, G
中科院分区：
文献类型：
--
作者：
Kosek, E;Ordeberg, G
为探讨慢性伤害性疼痛对躯体感觉的影响，对14例疼痛性髋关节炎患者的最痛区和相应对侧进行了定量感觉测试。12名患者在术后6-14个月的无痛状态下进行了重新评估。Von Frey细丝用于测试低阈值机械感受功能。使用压力痛觉计评估压迫性疼痛敏感性，使用Thermotest（R）评估热敏感性。在类似的时间间隔，在相应的地区检查性别和年龄匹配的对照。两组在对轻触和无害寒冷的敏感性方面没有统计学显著差异。与对照组相比，患者在手术前对最疼痛区域的压迫性疼痛敏感性增加（p < 0.002），对无害的温暖敏感性增加（p < 0.03），对冷痛敏感性增加（p < 0.05），对热痛敏感性增加（p = 0.054）。在疼痛区域，与手术前的值相比，患者对压迫疼痛的敏感性降低（p < 0.04），并且保持在正常范围内，对轻触的敏感性增加（p < 0.006）。手术后两组间无统计学显著差异，表明慢性伤害性疼痛维持了敏感性变化。(C)2000年国际疼痛研究协会欧洲分会联合会。
To investigate the effect of chronic nociceptive pain on somatosensory perception, quantitative sensibility testing was performed in the most painful area and the homologous contralateral side in 14 patients with painful osteoarthritis of the hip. Twelve patients were reassessed in a painfree state 6-14 months following surgery. Von Frey filaments were used to test low-threshold mechanoreceptive function. Pressure pain sensitivity was assessed with a pressure algometer and thermal sensitivity with a Thermotest(R). Sex- and age-matched controls were examined in the corresponding areas at similar time intervals. There was no statistically significant difference between groups in the sensitivity to light touch and innocuous cold in either session. Compared to controls, patients had increased sensitivity to pressure pain in the most painful area (p < 0.002), bilaterally increased sensitivity to innocuous warmth (p < 0.03), cold pain (p < 0.05) and a tendency toward bilaterally increased sensitivity to heat pain (p = 0.054) before surgery. In the painful area, patients' sensitivity to pressure pain decreased (p < 0.04) and, remaining within normal limits, sensitivity to light touch increased (p < 0.006) compared to values prior to surgery. No statistically significant differences between the groups were seen following surgery, indicating that the sensibility changes had been maintained by chronic nociceptive pain. (C) 2000 European Federation of Chapters of the International Association for the Study of Pain.