Soda lime adsorption of isoflurane and enflurane.
Soda lime adsorption of isoflurane and enflurane.
复制标题
碱石灰吸附异氟醚和安氟醚。
作者：
W. Grodin;M. Epstein;R. A. Epstein
作者证明，碱石灰会吸附安氟醚或异氟醚，其吸附量与碱石灰的水含量有关。将不同体积的液体安氟醚或异氟醚放入含有新鲜（按重量计15%水）或干燥钠石灰的平衡烧瓶中，并绘制气相麻醉剂浓度。当使用干钠石灰时，浓度与所添加液体体积的函数关系图是双相的：最初平坦，然后线性上升。这与之前报道的氟烷数据在质量上相似。作者假设干燥碱石灰会产生类似分子筛的结构，因为对于碳链长度和动力学直径较小的分子或具有顺式/反式异构等结构特征的分子来说，吸附效果最大，从而有效地减小了分子尺寸。
The authors demonstrated that soda lime will adsorb enflurane or isoflurane as a function of the water content of the soda lime. Various volumes of liquid enflurane or isoflurane were placed in an equilibration flask containing fresh (15% water by weight) or dried soda lime and the vapor phase anesthetic concentrations plotted. When dry soda lime was used, the plot of concentration as a function of volume of liquid added was biphasic: initially flat and then rising linearly. This is qualitatively similar to data reported previously for halothane. The authors hypothesize that drying soda lime produces a molecular sieve-like structure, as adsorption is greatest for molecules with small carbon chain lengths and kinetic diameters, or with structural characteristics such as cis/trans isomerism, which effectively reduce molecular size.