Comparison of ethyl glucuronide in hair with carbohydrate-deficient transferrin in serum as markers of chronic high levels of alcohol consumption
Comparison of ethyl glucuronide in hair with carbohydrate-deficient transferrin in serum as markers of chronic high levels of alcohol consumption
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DOI：
10.1016/j.forsciint.2009.04.003
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发表时间：
2009-07-01
影响因子：
2.2
通讯作者：
Polettini, Aldo
中科院分区：
文献类型：
--
作者：
Morini, Luca;Politi, Lucia;Polettini, Aldo
本研究旨在比较头发中葡萄糖醛酸乙酯（HEtG）和血清中缺乏碳水化合物的转铁蛋白（CDT）作为重度饮酒标志物的敏感性和特异性。86名志愿者，包括禁酒者、社交者和重度饮酒者，接受了采访，评估他们在过去2周和3个月期间的乙醇每日摄入量（EDI）。HEtG测定采用完全有效的LC-MS-MS程序，范围从
This study was designed with the aim to compare sensitivity and specificity of ethyl glucuronide in hair (HEtG) and carbohydrate-deficient transferrin (CDT) in serum as markers of heavy drinking. Eighty-six volunteers, including teetotalers, social, and heavy drinkers, were interviewed to evaluate their ethanol daily intake (EDI) during the last 2-week and 3-month periods. HEtG determination was performed by a fully validated LC-MS-MS procedure and ranged from