EFFECT OF ENVIRONMENTAL-TEMPERATURE AND PHOTOPERIOD ON THE MELATONIN LEVELS IN THE PINEAL, LATERAL EYE, AND PLASMA OF THE FROG, RANA-PEREZI - IMPORTANCE OF OCULAR MELATONIN
EFFECT OF ENVIRONMENTAL-TEMPERATURE AND PHOTOPERIOD ON THE MELATONIN LEVELS IN THE PINEAL, LATERAL EYE, AND PLASMA OF THE FROG, RANA-PEREZI - IMPORTANCE OF OCULAR MELATONIN
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DOI：
10.1016/0016-6480(89)90006-3
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发表时间：
1989-07-01
影响因子：
2.7
通讯作者：
VIVIENROELS, B
中科院分区：
文献类型：
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作者：
DELGADO, MJ;VIVIENROELS, B
研究了在2月和7月在长（18L：6D）光周期和高（25 . ±. 1.度）或低（6 . ±. 1.度）温度，以评估这些环境因素的影响。当青蛙保持在短光周期和低温下，在二月，没有褪黑激素的节奏观察松果体，眼组织，和血浆。高温在这一时期的一年中诱导的昼夜节律褪黑激素水平的侧眼和血浆。在7月，在长光周期和高温下，动物的松果体，眼睛和血浆中的褪黑激素表现出明显的节律。环境温度的降低，在这个季节取消褪黑激素的节奏。当动物在8月维持在高（25 . ±. 1.度）温度和长（18L：6D）或短（6L：18D）光周期，高夜间眼部褪黑激素水平的持续时间与暗相的长度相关。在所有实验中，眼部褪黑激素浓度很高，并且眼部褪黑激素谱和循环褪黑激素谱之间观察到的密切平行性表明，在该物种中，褪黑激素可以在全身循环中从眼睛释放。
Day-night melatonin concentrations were studied in the pineal body, lateral eye, and plasma of the frog Rana perezi in animals maintained in February and July under long (18L:6D) photoperiod and high (25 .+-. 1.degree.) or low (6 .+-. 1.degree.) temperature in order to evaluate the influence of these environmental fctors. When frogs were kept under short photoperiod and low temperature in February, no melatonin rhythm was observed in the pineal, ocular tissue, and plasma. High temperature at this period of the year induced a day-night rhythm of melatonin levels in the lateral eye and plasma. In July, under long photoperiod and high temperature, animals showed pronounced rhythms of melatonin in the pineal, eye, and plasma. A decrease of environmental temperature in this season abolished the melatonin rhythm. When animals were maintained in August under high (25 .+-. 1.degree.) temperature and long (18L:6D) or short (6L:18D) photoperiod, the duration of high night time ocular melatonin levels was correlated to the length of the dark phase. In all experiments the high ocular melatonin concentrations and the close parallelism observed between ocular and circulating melatonin profiles suggest that in this species melatonin could be released from the eyes in the general circulation.