Wearable, Luminescent Oxygen Sensor for Transcutaneous Oxygen Monitoring.
Wearable, Luminescent Oxygen Sensor for Transcutaneous Oxygen Monitoring.
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用于经皮氧监测的可穿戴发光氧传感器。
DOI：
10.1021/acsami.8b13276
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发表时间：
2018
影响因子：
9.5
通讯作者：
Jin
中科院分区：
文献类型：
--
作者：
Changduk Lim;Soyeon Lee;Jin;Hye;Yu;Jin
将发光气体传感技术与可穿戴设备相结合，提出了一种用于经皮氧分压监测的可穿戴氧气传感器的新概念。鉴于氧气监测在诊断各种疾病中的核心作用，人们对其进行了详尽的研究。为了充分理解与正常生理和病理条件相关的机制，需要能够量化从亚细胞到宏观水平的O2的生理分布和实时动态。尽管氧气具有深远的生物学和临床重要性，但在生理环境中非侵入性地定量氧气的有效方法很少。这里开发的可穿戴传感器由三个组件组成：通过碳带附着在皮肤上的发光传感膜、作为光源的有机发光二极管(OLED)和作为光探测器的有机光电二极管(OPD)。所有组件都是可溶液加工的，并以绷带状的配置集成在一个平面上。为了验证性能，使用可穿戴传感器测量了压力诱导咬合时小臂和拇指的tcpO2变化，并与商业仪器测量的结果进行了比较。除了灵活性之外，该传感器的其他功能使其成为一种潜在的低成本解决方案，可以同时监测身体任何部位的tcpO2。
We present a new concept for a wearable oxygen (O2) sensor for transcutaneous O2 pressure (tcpO2) monitoring by combining the technologies of luminescent gas sensing and wearable devices. O2 monitoring has been exhaustively studied given its central role in diagnosing various diseases. The ability to quantify the physiological distribution and real-time dynamics of O2 from the subcellular to the macroscopic level is required to fully understand mechanisms associated with both normal physiological and pathological conditions. Despite its profound biological and clinical importance, few effective methods exist for noninvasively quantifying O2 in a physiological setting. The wearable sensor developed here consists of three components: a luminescent sensing film attached onto skin by a carbon tape, an organic light-emitting diode (OLED) as a light source, and an organic photodiode (OPD) as a light detector. All the components are solution-processable and integrated on a plane in a bandage-like configuration. To verify the performance, tcpO2 variations by pressure-induced occlusion were measured in the lower arm and a thumb by the wearable sensor, and the results were comparable to those measured by a commercial instrument. In addition to its flexibility, other features of this sensor render it a potential low-cost solution for the simultaneous monitoring of tcpO2 in any part of a body.
基于 CMOS 埋入式双结光电二极管的无滤波器光学氧传感器。
DOI：
10.1016/j.snb.2012.07.046
发表时间：
2013
期刊：
Sensors and actuators. B, Chemical
影响因子：
--
作者：
Zhan,Zhiyong;Zhou,Bin;Fu,Zhenhong;Bright,FrankV;Cartwright,AlexanderN;Bartsch,CarrieM;Titus,AlbertH
通讯作者：
Titus,AlbertH