Exploring the cooccurrence of behavioural phenotypes for avoidant/restrictive food intake disorder in a partial hospitalization sample
Exploring the cooccurrence of behavioural phenotypes for avoidant/restrictive food intake disorder in a partial hospitalization sample
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DOI：
10.1002/erv.2670
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发表时间：
2019-07-01
影响因子：
5.3
通讯作者：
Menzel, Jessie E.
中科院分区：
文献类型：
--
作者：
Reilly, Erin E.;Brown, Tiffany A.;Menzel, Jessie E.
目的提供回避/限制性食物摄入障碍（ARFID）临床特征的文献提出了拒绝食物的三种功能：害怕负面后果、缺乏饥饿或感觉敏感性。最近的研究表明，这些功能可用于ARFID患者的亚型；然而，其他研究表明，这些类别并不是相互排斥的，而是代表了可以共同发生的神经生物学维度。目前的研究探讨了ARFID患者出现部分住院计划的潜在行为表型的共同发生。方法对2014年6月至2018年5月就诊的ARFID患者（N = 59）进行回顾性图表分析。结果对于与行为表型一致的症状的同时发生，评分者表现出非常好的一致性，超过50%的样本认可症状与一种以上的表型一致。感觉敏感性表型在样本中最常见，并且经常与其他两种表型同时发生。结果表明，一个人体内可能存在多种食物避免功能。未来的工作应旨在进一步表征个体呈现单一与多重表型特征。
Objective Literature providing clinical characterizations of avoidant/restrictive food intake disorder (ARFID) has proposed the occurrence of three functions for food refusal: fear of negative consequences, lack of hunger, or sensory sensitivity. Recent studies have suggested that these functions may be used to subtype patients presenting with ARFID; however, other work suggests that these categories are not mutually exclusive and instead represent neurobiological dimensions that can cooccur. The current study explored the potential cooccurrence of behavioural phenotypes in patients with ARFID presenting to a partial hospitalization program. Method Two raters conducted a retrospective chart review of patients with ARFID presenting to treatment from June 2014 to May 2018 (N = 59). Results Regarding cooccurrence of symptoms consistent with behavioural phenotypes, raters showed excellent agreement, and over 50% of the sample endorsed symptoms consistent with more than one phenotype. The sensory sensitivity phenotype was most common in the sample and frequently cooccurred with both other phenotypes. Discussion Results suggest that multiple functions for food avoidance may be present within one individual. Future work should aim to further characterize individuals presenting with singular versus multiple phenotype characteristics.