Differentiating between atypical adenomatous hyperplasia and bronchioloalveolar carcinoma using the computed tomography number histogram
Differentiating between atypical adenomatous hyperplasia and bronchioloalveolar carcinoma using the computed tomography number histogram
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DOI：
10.1016/s0003-4975(03)00729-x
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发表时间：
2003-09-01
影响因子：
4.6
通讯作者：
Suemasu, K
中科院分区：
文献类型：
--
作者：
Nomori, H;Ohtsuka, T;Suemasu, K
背景资料。不典型腺瘤性增生(AAH)和细支气管肺泡癌(BAC)在CT上均表现为磨玻璃样阴影(GGO)，有时难以鉴别。为了帮助区分两者，我们检查了他们的CT数字组织图。绘制AAH(n=9)和非粘液性BAC(n=8)的像素CT数直方图，并量化直方图上的峰值和平均CT数。结果。虽然AAH和BAC的病灶大小无明显差异，但AAH的直径均小于或等于1 cm。所有AAHS和BAC均表现为一个直方图峰值。直方图上AAH值和平均CT值均显著低于BAC值(p<；0.001)。然而，AAH和BAC之间的重叠程度，峰值CT数小于平均CT数。直方图上的峰值CT数有助于AAH和BAC的鉴别诊断。CT数字直方图诊断为AAH的直径小于或等于1 cm的GGO病变可安全地进行CT随访。(C)2003年，由胸外科医生学会提供。
Background. Both atypical adenomatous hyperplasia (AAH) and bronchioloalveolar carcinoma (BAC) appear as ground glass opacity (GGO) lesions by computed tomography (CT) and are sometimes difficult to differentiate. To aid distinction between the two, we examined their CT number histograms.Methods. Histograms of pixel CT numbers were made for AAH (n = 9) and nonmucinous BAC (n = 8), and the peak and mean CT numbers on the histogram were quantified. Results. Although there was no significant difference in lesion size between AAH and BAC, all AAHs were less than or equal to 1 cm in diameter. All AAHs and BACs manifested one histogram peak. Both the peak and mean CT numbers on the histogram were significantly lower for AAH than for BAC (p < 0.001). However, the degree of overlap between AAH and BAC was less for the peak CT number than for the mean CT number.Conclusions. The peak CT number on the histogram can help the radiologic differentiation between AAH and BAC. GGO lesions less than or equal to 1 cm in diameter that are diagnosed as AAH from the CT number histogram can be safely followed by CT. (C) 2003 by The Society of Thoracic Surgeons.