Bio-functionalization of metal-organic frameworks by covalent protein conjugation
Bio-functionalization of metal-organic frameworks by covalent protein conjugation
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DOI：
10.1039/c0cc03288c
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发表时间：
2011-01-01
影响因子：
4.9
通讯作者：
Park, Seongsoon
中科院分区：
文献类型：
--
作者：
Jung, Suhyun;Kim, Youngmee;Park, Seongsoon
功能蛋白质到金属有机框架（MOFs）上的生物缀合已经通过活化MOFs表面上的有机连接基的侧链连接基团来实现。荧光显微镜显示增强的荧光蛋白成功地缀合到MOFs上。此外，抗坏血酸-脂肪酶-B-缀合的MOFs在（+/-）-1-苯基乙醇的酯交换中没有表现出对映选择性和活性的损失。
Bioconjugation of functional proteins onto metal-organic frameworks (MOFs) has been achieved using activation of pendent linking groups of the organic linkers on the surface of MOFs. Fluorescent microscopy revealed successful conjugation of an enhanced fluorescent protein onto MOFs. In addition, Candida-antarctica-lipase-B-conjugated MOFs showed no loss of enantioselectivity and activity in transesterification of (+/-)-1-phenylethanol.