Comparative micromorphologic in vitro porcine study of IntraLase and Femto LDV femtosecond lasers
Comparative micromorphologic in vitro porcine study of IntraLase and Femto LDV femtosecond lasers
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DOI：
10.1016/j.jcrs.2008.04.037
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发表时间：
2008-08-01
影响因子：
2.8
通讯作者：
Oberheide, Uwe
中科院分区：
文献类型：
--
作者：
Kermani, Omid;Oberheide, Uwe
目的：评价德国科隆Augenklinik am Neumarkt准分子激光原位角膜磨镶术中2种飞秒屈光手术激光的角膜瓣形成和基质床质量。方法：采用60 kHzIntraLase FS激光(先进医学光学)和Femto LDV飞秒激光原型(Ziemer眼科系统公司)在115只新鲜猪眼上制作角膜瓣。评估的参数包括减去厚度的实际厚度与预期厚度、切割和总抽吸时间、瓣边缘质量和瓣床平整度。结果：60 kHzIntraLase FS激光切割时间为31秒，Femto LDV激光切割时间为38秒。使用这两种激光器，所实现的翼片厚度与预期的翼片厚度的标准偏差很小(分别为136µm+/-10和130+/-9µm)。光镜下观察，使用IntraLase的基质床质量稍好。IntraLASE和Femto LDV的床面粗糙度RMS分别为1.6+/-0.5微米和2.0+/-0.4微米。两种激光都没有在基质床的相邻组织层显示明显的热或机械损伤。结论：IntraLase FS和Femto LDV飞秒激光器的激光切割同样光滑，质量也很好。在两种系统中，皮瓣厚度的标准差都很小且相等。
PURPOSE: To assess flap creation and stromal bed quality of 2 femtosecond refractive surgery lasers in laser in situ keratomileusis.SETTING: Augenklinik am Neumarkt, Cologne, Germany.METHODS: Corneal flaps were created in 115 freshly enucleated porcine eyes using the 60 kHz IntraLase FS laser(Advanced Medical Optics) and a prototype model of the Femto LDV femtosecond laser (Ziemer Ophthalmic Systems AG). The parameters that were evaluated included actual versus intended thickness by subtraction pachymetry, cutting and total suction time, quality of flap edges, and smoothness of flap beds. Confocal microscopy (Atos PL mu [Altos GmbH]) was used to objectively determine the root mean square (RMS) of the surface roughness of the stromal bed.RESULTS: Cutting time was 31 seconds for the 60 kHz IntraLase FS laser and 38 seconds for the Femto LDV laser. With both lasers, the standard deviation in achieved versus intended flap thickness was small (136 mu m +/- 10 and 130 +/- 9 mu m, respectively). Under micromorphologic examination, stromal bed quality was slightly better with the IntraLase. The RMS of bed roughness was 1.6 +/- 0.5 mu m with the IntraLase and 2.0 +/- 0.4 mu m with the Femto LDV. Neither laser showed significant thermal or mechanical damage in adjacent tissue layers of the stromal bed. The laser-induced bubble layer was more pronounced with the IntraLase.CONCLUSION: The laser cuts of the IntraLase FS and Femto LDV femtosecond lasers were equally smooth and of excellent quality. The standard deviation of the flap thickness was small and equal in both systems.