Influence of intraocular lens material on regeneratory posterior capsule opacification after neodymium: YAG laser capsulotomy

Influence of intraocular lens material on regeneratory posterior capsule opacification after neodymium: YAG laser capsulotomy
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DOI:
10.1016/s0886-3350(03)00345-6
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发表时间:
2003-08-01
影响因子:
2.8
通讯作者:
Rainer, G
Rainer, G
中科院分区:
医学2区
文献类型:
--
作者:
Georgopoulos, M;Findl, O;Rainer, G

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目的:评价Nd:YAG(Nd:YAG)激光晶状体囊切开术对剩余周围后囊膜再生混浊的形态和发展的影响。设置:维也纳大学医学院眼科,奥地利维也纳。方法:在Nd:YAG激光晶状体囊切开术前和后即刻以及1周、6个月和1 ~ 3年连续38例患者中拍摄标准化数字后照明照片。评价再生性后囊膜混浊(PCO)和囊切开术开口周围混浊的变化。评估了人工透镜(IOL)材料类型和设计(丙烯酸,n = 8;水凝胶,n = 8;硅胶开放襻,n = 11;硅胶支撑襻板,n = 6;聚(甲基丙烯酸甲酯)[PMMA],n = 5)的影响。结果:在17只植入硅凝胶人工晶状体的眼中,有8只观察到再生性PCO减少。Nd:YAG晶状体囊切开术边缘的大量珍珠形成是硅胶IOL的典型情况(8只眼),但也发生在PMMA IOL中。植入丙烯酸IOL的眼在晶状体囊切开术后再生性PCO没有变化。8眼水凝胶IOL的后囊切开术开口完全关闭。结论:Neopolymer:YAG激光囊切开术引起再生性PCO的发展和形态的变化。硅胶和PMMA IOL导致囊切开术边缘显著的珍珠形成,通常伴有外周再生性PCO(硅胶)减少。水凝胶IOL导致Nd:YAG晶状体囊切开术开口再闭合的发生率较高。(C)2003年ASCRS和ESCRS。
Purpose: To evaluate the influence of a neodymium:YAG (Nd:YAG) laser capsulotomy on the morphology and development of regeneratory opacification of the remaining surrounding posterior capsule.Setting: Department of Ophthalmology, Medical School, University of Vienna, Vienna, Austria.Methods: Standardized digital retroillumination photographs were taken immediately before and after Nd:YAG laser capsulotomy and at 1 week, 6 months, and 1 to 3 years in 38 eyes of consecutive patients. Changes in regeneratory posterior capsule opacification (PCO) and opacification around the capsulotomy opening were evaluated. The influence of the type of intraocular lens (IOL) material and design (acrylic, n = 8; hydrogel, n = 8; silicone open loop, n = 11; silicone plate haptic, n = 6; poly(methyl methacrylate) [PMMA], n = 5) was assessed. The state of the anterior vitreous surface was examined at the slitlamp in all eyes.Results: In 8 of 17 eyes with a silicone IOL, reduced regeneratory PCO was observed. Massive pearl formation on the margin of the Nd:YAG capsulotomy was typical with silicone IOLs (8 eyes) but also occurred with PMMA IOLs. Eyes with acrylic IOLs had no change in regeneratory PCO after the capsulotomy. Three of 8 eyes with hydrogel IOLs had complete closure of the posterior capsulotomy opening.Conclusions: Neodymium:YAG laser capsulotomy induced changes in the development and morphology of regeneratory PCO. Silicone and PMMA IOLs led to significant pearl formation on the capsulotomy margin, often combined with a reduction of peripheral regeneratory PCO (silicone). Hydrogel IOLs led to a higher incidence of reclosure of the Nd:YAG capsulotomy opening. (C) 2003 ASCRS and ESCRS.