Could sudden sensorineural hearing loss be the sole manifestation of COVID-19? An investigation into SARS-COV-2 in the etiology of sudden sensorineural hearing loss
Could sudden sensorineural hearing loss be the sole manifestation of COVID-19? An investigation into SARS-COV-2 in the etiology of sudden sensorineural hearing loss
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DOI：
10.1016/j.ijid.2020.06.023
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发表时间：
2020-08-01
影响因子：
8.4
通讯作者：
Cetin, Ferihan
中科院分区：
文献类型：
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作者：
Kilic, Osman;Kalcioglu, Mahmut Tayyar;Cetin, Ferihan
目的：本研究旨在调查在 COVID-19 大流行期间仅出现突发感音神经性听力损失（SSHNL）的患者中是否存在严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）。方法：该研究纳入了 2020 年 4 月 3 日至 12 日期间到耳鼻喉科门诊就诊的 5 名仅主诉单侧 SSNHL 的男性患者。这些患者被转诊至传染病诊所，实时评估 SARS-CoV-2 的情况。聚合酶链反应（RTPCR）检测。结果：其中一名患者的 SARS-CoV-2 RT-PCR 检测呈阳性，其他四名患者呈阴性。注意到 SARS-CoV-2 阳性 SSNHL 患者对 COVID-19 特异性治疗有积极反应。结论：应该记住，SSNHL 等非特异性症状可能是识别 COVID-19 病例的唯一体征。在这次大流行期间，认识到 COVID-19 患者的这种非特异性表现对于通过隔离和及早开始 COVID-19 针对性治疗来防止感染传播至关重要。 (C) 2020 作者。由爱思唯尔有限公司代表国际传染病学会出版。这是一篇遵循 CC BY-NC-ND 许可证 (http://creativecommons.org/licenses/by-ncnd/4.0/) 的开放获取文章。
Objective: This study aimed to investigate the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in patients presenting with only sudden sensorineural hearing loss (SSHNL) during the COVID-19 pandemic.Methods: The study included five male patients who presented with the sole complaint of unilateral SSNHL to the otolaryngology outpatient clinic between 03-12 April 2020. The patients were referred to the infectious diseases clinic to be evaluated for SARS-CoV-2 by real time polymerase chain reaction (RTPCR) testing.Results: RT-PCR testing for SARS-CoV-2 was positive in one of the patients and negative in the other four patients. A positive response to COVID-19-specific treatment in the SARS-CoV-2 positive SSNHL patient was noted.Conclusion: It should be remembered that non-specific symptoms such as SSNHL could be the only sign with which to recognize a COVID-19 case. Awareness of such a non-specific presentation of COVID-19 patients is crucial during this pandemic period for preventing infectious spread through isolation and early initiation of COVID-19 targeted treatment. (C) 2020 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-ncnd/4.0/).