Effect of very low nicotine content cigarettes on alcohol drinking and smoking among adult smokers who are at-risk alcohol drinkers.
Effect of very low nicotine content cigarettes on alcohol drinking and smoking among adult smokers who are at-risk alcohol drinkers.
复制标题
尼古丁含量极低的香烟对有饮酒风险的成年吸烟者饮酒和吸烟的影响。
DOI：
10.1037/pha0000603
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发表时间：
2023
影响因子：
2.3
通讯作者：
Coleman-Cowger,VictoriaH
中科院分区：
文献类型：
--
作者：
Peters,EricaN;Pickworth,WallaceB;Monahan,Erin;Smith,CarsonE;Triplett,CherylA;Coleman-Cowger,VictoriaH
酒精和烟草的使用是相互关联的。本研究通过问题饮酒来检测极低尼古丁含量（VLNC）和中等尼古丁含量（MNC）香烟的反应。我们在两组成年吸烟者中采用VLNC和MNC香烟的双盲、随机、受试者内交叉设计：有风险饮酒（ARD; n= 23）和无ARD（n= 24）。参与者在他们的家庭环境中仅吸烟他们指定的实验香烟7天，并在每个实验周的开始和结束时完成实验室访问，包括随意吸烟指定的实验香烟。参与者在两种条件之间吸烟7天。参与者提供了酒精和香烟消费的每日报告。在基线和每个实验周结束时评估当前精神障碍诊断和统计手册-第5版（DSM-5）酒精使用障碍（AUD）。实验香烟的吸烟依从性良好。调整基线饮酒，实验香烟或ARD组对每天饮酒或饮酒欲望没有显着影响。在实验室吸烟期间，实验香烟或ARD组对每天的香烟数量或任何抽吸地形图结果或吸烟后呼出的一氧化碳没有影响。无受试者的AUD状态或AUD严重程度发生变化。暴露于VLNC香烟7天后，患有ARD的成年吸烟者未表现出代偿性饮酒或代偿性吸烟行为。美国未来减少香烟中尼古丁含量的政策变化可能不会在这一脆弱和普遍的吸烟人群中产生非预期的补偿性饮酒或吸烟。（PsycInfo数据库记录（c）2023阿帕，保留所有权利）
Alcohol and tobacco use are interrelated. This study examined response to very low nicotine content (VLNC) and moderate nicotine content (MNC) cigarettes by problematic drinking. We utilized a double-blind, randomized, within-subjects crossover design of VLNC and MNC cigarettes in two groups of adult cigarette smokers: with at-risk drinking (ARD; n= 23) and without ARD (n= 24). Participants smoked only their assigned experimental cigarette in their home environment for 7 days, and completed laboratory visits, including ad libitum smoking of the assigned experimental cigarette, at the beginning and end of each experimental week. Participants smoked their usual cigarettes for 7 days between conditions. Participants provided daily reports of alcohol and cigarette consumption. Current Diagnostic and Statistical Manual of Mental Disorders–5th edition (DSM-5) alcohol use disorder (AUD) was assessed at baseline and the end of each experimental week. Compliance with smoking of experimental cigarettes was good. Adjusting for baseline drinking, there was no significant effect of experimental cigarette or ARD group on drinks per day or alcohol urges. There was no effect of experimental cigarette or ARD group on cigarettes per day, or on any puff topography outcome or postsmoking exhaled carbon monoxide during laboratory smoking. No participant had a change in AUD status or AUD severity. After 7 days of exposure to VLNC cigarettes, adult cigarette smokers with ARD did not show compensatory drinking or compensatory smoking behavior. A future policy change in the United States to reduce nicotine content in cigarettes may not produce unintended compensatory drinking or smoking among this vulnerable and prevalent population of smokers.(PsycInfo Database Record (c) 2023 APA, all rights reserved)