Biochemical markers in oral submucous fibrosis: A review and update
Biochemical markers in oral submucous fibrosis: A review and update
复制标题
口腔粘膜下纤维化的生化标志物：回顾和更新
作者：
V. Kamath;K. Satelur;Y. Komali
口腔粘膜下纤维性变（OSMF）是一种潜在的恶性口腔疾病，与咀嚼槟榔的习惯有关。自20世纪50年代首次描述以来，已报道了许多流行病学，生物化学，组织学和遗传学研究。虽然大多数研究指出槟榔的原因和影响，但共同添加剂因素也涉及这种情况的进展和恶性转化。生化研究集中在概述这些患者的血液，血清或组织中的这种变化，并对OSMF的可能发病机制提供了见解。本文试图汇编详细的生化调查OSMF和总结和推断的结果。
Oral submucous fibrosis (OSMF) is a potentially malignant oral condition effectively linked to the causative habit of chewing areca nut. Since its first description in the 1950s, numerous epidemiological, biochemical, histological, and genetic studies have been reported. While most studies point out to the cause and effect of areca nut, co-additive factors are also implicated in the progression and malignant transformation of this condition. Biochemical investigations have concentrated on outlining such changes in the blood, serum or tissues of these patients and have given insights on the possible pathogenesis of OSMF. This article attempts to compile details of biochemical investigations in OSMF and summarize and infer on the findings.