SYNAPTIC ORGANIZATION OF MOTOR CORTICOSTRIATAL PROJECTIONS IN THE RAT

SYNAPTIC ORGANIZATION OF MOTOR CORTICOSTRIATAL PROJECTIONS IN THE RAT
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DOI:
10.1016/0014-4886(81)90221-1
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发表时间:
1981-01-01
影响因子:
5.3
通讯作者:
KULTASILINSKY, K
KULTASILINSKY, K
中科院分区:
医学2区
文献类型:
--
作者:
COSPITO, JA;KULTASILINSKY, K

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通过光学显微镜和电子显微镜确定大鼠运动皮质纹状体投射的精确组织。运动皮质(头部、前肢、躯干和后肢区域)要么通过手术切除,要么注射[3H]亮氨酸。描述了纹状体的末端区域,并对具有最密集末端变性或轴突标记的区域进行取芯和处理以进行电镜处理。运动区的投射主要终止于背外侧纹状体、前连合的喙部和苍白球的外侧。来自运动皮层突触的轴突专门位于这些区域的小树突的树突棘上。
The precise organization of motor corticostriate projections in rats was determined by light microscopy and EM. The motor cortex (head, forelimb, trunk and hind limb regions) was either surgically ablated or injected with [3H]leucine. Terminal fields in the striatum were described and regions with the densest terminal degeneration or axonal labeling were cored and processed for EM. Projections from the motor region end mainly in the dorsolateral striatum, rostral to the anterior commissure and lateral to the pallidum. Axons from the motor cortex synapse exclusively on dendritic spines of small dendrites in these regions.