Material properties of articular cartilage in the rabbit tibial plateau
Material properties of articular cartilage in the rabbit tibial plateau
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DOI：
10.1016/j.jbiomech.2005.07.017
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发表时间：
2006-01-01
影响因子：
2.4
通讯作者：
Beynnon, Bruce D.
中科院分区：
文献类型：
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作者：
Roemhildt, Maria L.;Coughlin, Kathryn M.;Beynnon, Bruce D.
采用双相压痕蠕变实验测定兔胫骨平台关节软骨的材料特性。使用定制的材料测试仪在每个隔室内的两个位置对大约4个月龄和大于12个月龄的兔的配对后肢软骨标本进行了测试。采用三因素方差分析方法，分析了不同小腿、不同骨间隔和不同测试位置对每组标本的材料特性(骨料模数、渗透率和泊松比)和软骨厚度的影响。虽然左右腿之间的软骨特性没有差异，但每组标本间存在差异。对于青少年组的软骨，内侧室的骨料模量值比外侧室低40%，而内侧室的渗透性和厚度的值比外侧室大(分别为57%和30%)。内侧间隙的泊松比比外侧间隙小19%。在成熟组的软骨中也观察到类似的结果，内侧间隙的渗透性和厚度的值比外侧间隙的值(分别为66%和34%)更大。内侧间隙的泊松比比外侧间隙小22%。(C)2005爱思唯尔有限公司。保留所有权利。
The material properties of articular cartilage in the rabbit tibial plateau were determined using biphasic indentation creep tests. Cartilage specimens from matched-pair hind limbs of rabbits approximately 4 months of age and greater than 12 months of age were tested on two locations within each compartment using a custom built materials testing apparatus. A three-way ANOVA was used to determine the effect of leg, compartment, and test location on the material properties (aggregate modulus, permeability, and Poisson's ratio) and thickness of the cartilage for each set of specimens.While no differences were observed in cartilage properties between the left and right legs, differences between compartments were found in each set of specimens. For cartilage from the adolescent group, values for aggregate modulus were 40% less in the medial compartment compared to the lateral compartment, while values for permeability and thickness were greater in the medial compartment compared to the lateral compartment (57% and 30%, respectively). Values for Poisson's ratio were 19% less in the medial compartment compared to the lateral compartment. There was also a strong trend for thickness to differ between test locations.Similar findings were observed for cartilage from the mature group with values for permeability and thickness being greater in the medial compartment compared to the lateral compartment (66% and 34%, respectively). Values for Poisson's ratio were 22% less in the medial compartment compared to the lateral compartment. (c) 2005 Elsevier Ltd. All rights reserved.