Megavoltage cone-beam CT: System description and clinical applications
Megavoltage cone-beam CT: System description and clinical applications
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DOI：
10.1016/j.meddos.2005.12.009
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发表时间：
2006-03-01
影响因子：
1.2
通讯作者：
Pouliot, J
中科院分区：
文献类型：
--
作者：
Morin, O;Gillis, A;Pouliot, J
在本文中，我们描述了一种临床巨压锥束计算机断层扫描（MV CBCT）系统，介绍了图像采集和患者设置过程，讨论了定位精度和图像质量，并通过选定的临床实例说明了其在图像引导放射治疗（IGRT）中的潜在应用。MV CBCT系统由一个标准直线加速器和一个非晶硅平板电子门户成像装置组成，该装置适用于兆电子伏（MeV）光子。集成的计算机工作空间提供投影图像的自动采集、图像重建、CT到CBCT图像配准和沙发移位计算。该系统具有亚毫米级的定位精度和足够的软组织分辨率，可以可视化前列腺等结构。在我们的临床中，我们使用MV CBCT系统来检测非刚性脊髓扭曲，监测肿瘤的生长和收缩，以及定位和定位肺中的静止肿瘤。MV CBCT也极大地改善了CT图像中受金属伪影影响的结构的描绘。MV CBCT在过去几年中经历了重大发展。目前的图像质量已经被证明足以满足许多IGRT应用。此外，随着成像技术的不断进步，我们预计MV CBCT的临床应用范围将会扩大。(c) 2006年美国医疗剂量测定师协会。
In this article, we describe a clinical mega-voltage cone-beam computed tomography (MV CBCT) system, present the image acquisition and patient setup procedure, discuss the positioning accuracy and image quality, and illustrate its potential use for image-guided radiation therapy (IGRT) through selected clinical examples. The MV CBCT system consists of a standard linear accelerator equipped with an amorphous-silicon flat panel electronic portal-imaging device adapted for mega-electron volt (MeV) photons. An integrated computer workspace provides automated acquisition of projection images, image reconstruction, CT to CBCT image registration, and couch shift calculation. The system demonstrates submillimeter localization precision and sufficient soft-tissue resolution to visualize structures such as the prostate. In our clinic, we have used the MV CBCT system to detect nonrigid spinal cord distortions, monitor tumor growth and shrinkage, and locate and position stationary tumors in the lung. MV CBCT has also greatly improved the delineation of structures in CT images that suffer from metal artifacts. MV CBCT has undergone significant development in the last few years. Current image quality has already proven sufficient for many IGRT applications. Moreover, we expect the range of clinical applications for MV CBCT to grow as imaging technology continues to improve. (c) 2006 American Association of Medical Dosimetrists.