Organic Superbases: The Concept at a Glance
Organic Superbases: The Concept at a Glance
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DOI：
10.1055/s-0033-1340059
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发表时间：
2013-12-02
期刊：
影响因子：
2
通讯作者：
Harwood, Laurence M.
中科院分区：
文献类型：
--
作者：
Ishikawa, Tsutomu;Harwood, Laurence M.
术语“超强碱”通常应用于经历不可逆质子提取的含离子金属的碱。然而，脒、胍、磷腈和Verkade碱的非离子强力胺衍生物具有与1，8-双（二甲氨基）萘相当或更高的碱度，它们都可以被任意地分类为有机超强碱。这个集群包含的手稿介绍了有机超碱的最新进展，包括它们在有机合成中的应用，但在继续之前，让我们考虑一下什么样的分子构成了有机超碱。
The term 'super base' is generally applied to ionic metal-containing bases that undergo irreversible proton abstraction. However, non-ionic powerful amine derivatives of amidines, guanidines, phosphazenes, and Verkade's bases with comparable or higher basicity to that of 1,8-bis(dimethylamino)naphthalene can all be arbitrarily classified as organic superbases. This Cluster contains manuscripts that present recent progress on organic superbases, including their applications in organic synthesis but, before proceeding, let us consider what class of molecule constitutes an organic superbase.