THE BARBADOS EYE STUDY - PREVALENCE OF OPEN-ANGLE GLAUCOMA
THE BARBADOS EYE STUDY - PREVALENCE OF OPEN-ANGLE GLAUCOMA
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DOI：
10.1001/archopht.1994.01090180121046
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发表时间：
1994-06-01
影响因子：
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通讯作者：
HYMAN, L
中科院分区：
文献类型：
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作者：
LESKE, MC;CONNELL, AMS;HYMAN, L
目的：描述巴巴多斯眼科研究的设计，并报告主要为黑人研究人群中开角型青光眼（GAG）的患病率。设计：基于人群的患病率研究。设置和参与者：西印度群岛巴巴多斯的居民，从巴巴多斯出生的40至84岁公民的简单随机样本中确定。数据收集：参与者有一个全面的研究访问，包括自动视野检查，压平眼压测量，眼底照相;有具体检查结果的人，以及10%的参与者样本，结果：OAG的诊断需要在排除其他原因后，根据青光眼损害的视野和视盘标准。结果：4709名参与者（占合格人数的83.5%）的人口统计学特征与人口普查人口相似。在研究中心接受测试的4631名参与者中，95%完成了Humphrey自动视野检查，97%进行了摄影或临床椎间盘分级;其中93%完成了眼科检查。在该成人人群中，黑人中自我报告的OAG患病率为7.0%（302/4314），混血人种为3.3%（6/184），白色或其他参与者为0.8%（1/133）。在黑人和混血参与者中，60岁及以上的患病率达到12%，男性（8.3%）高于女性（5.7%），年龄调整后的男女比例为1.4。此外，超过3%的参与者被归类为可疑OAG.Conclusions：据我们所知，巴巴多斯眼科研究是有史以来最大的青光眼研究在黑人人口中进行，并确定更多的人与OAG比以前任何人口研究。OAG的患病率很高，尤其是在老年人和男性中。在50岁或50岁以上的参与者中，每11人中就有1人患有OAG，70岁或70岁以上的患病率增加到每6人中有1人。研究结果突出了OAG在非洲-加勒比地区的公共卫生重要性，并对其他人群产生影响。
Objective: To describe the design of the Barbados Eye Study and report on the prevalence of open angle glaucoma (GAG) in a predominantly black study population.Design: Population-based prevalence study.Setting and Participants: Residents of Barbados, West Indies, identified from a simple random sample of Barbadian-born citizens 40 through 84 years old.Data Collection: Participants had a comprehensive study visit that included automated perimetry, applanation tonometry, and fundus photography; persons with specific examination findings, as well as a 10% sample of participants, were referred for an ophthalmologic examination and additional tests.Outcome: A diagnosis of OAG required both visual field and optic disc criteria for glaucoma damage after excluding other causes.Results: The 4709 participants (83.5% of those eligible) had demographic characteristics that were similar to the census population. Of the 4631 participants who were tested at the study site, 95% completed Humphrey automated perimetry and 97% had photographic or clinical disc gradings; 93% of those referred completed the ophthalmologic examination. In this adult population, the prevalence of OAG by self-reported race was 7.0% (302/4314) in black, 3.3% (6/184) in mixed-race, and 0.8% (1/133) in white or other participants. In black and mixed-race participants, the prevalence reached 12% at age 60 years and older and was higher in men (8.3%) than in women (5.7%), with an age-adjusted male-female ratio of 1.4. In addition, over 3% of the participants were classified as having suspect OAG.Conclusions: To our knowledge, the Barbados Eye Study is the largest glaucoma study ever conducted in a black population and identified more people with OAG than did any previous population study. The prevalence of OAG was high, especially at older ages and in men. Among participants 50 years old or older, one in 11 had OAG, and prevalence increased to one in six at age 70 years or older. The results highlight the public health importance of OAG in the Afro-Caribbean region and have implications for other populations.