ELIMINATION OF MICROFILARIAE (LITOMOSOIDES-CARINII FILARIOIDEA) IN THE PATENT AND IN THE IMMUNIZED COTTON-RAT
ELIMINATION OF MICROFILARIAE (LITOMOSOIDES-CARINII FILARIOIDEA) IN THE PATENT AND IN THE IMMUNIZED COTTON-RAT
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DOI：
10.1016/0035-9203(81)90046-8
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发表时间：
1981-01-01
影响因子：
2.2
通讯作者：
WENK, P
中科院分区：
文献类型：
--
作者：
HAAS, B;WENK, P
在感染卡氏Litomosoides carinii的棉鼠中，微丝蚴的周转在正常大鼠和通过皮下接种胚胎微丝蚴免疫的大鼠中大致相等。(The在具有稳定微丝蚴血症的大鼠中，每日周转量可能超过2 × 106。）在正常棉鼠中，微丝蚴似乎在胸膜腔（32%）、肺（39%）和肝、脾和肾（29%）中被消除。然而，在免疫的大鼠中，几乎所有的微丝蚴在到达血液之前就被消除，从而阻止了通畅;这种消除似乎发生在胸膜腔（97%）和肺（3%）中。霍金
In cotton rats infected withLitomosoides carinii, the turnover of microfilariae is more or less equal in normal rats and in rats which have been immunized by the subcutaneous inoculation of embryonic microfilariae. (The daily turnover is probably more than 2X106in a rat with a stable micro-filaraemia.) In normal cotton rats the microfilariae seem to be eliminated in the pleural cavity (32%), lungs (39%) and liver, spleen and kidneys (29%). In immunized rats, however, nearly all the microfilariae are eliminated before they reach the blood so that patency is prevented; this elimination seems to take place in the pleural cavity (97%) and in the lungs (3%).F. Hawking.