Panic disorder in patients with chronic heart failure
Panic disorder in patients with chronic heart failure
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DOI：
10.1016/j.jpsychores.2007.09.002
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发表时间：
2008-03-01
影响因子：
4.7
通讯作者：
Herzog, Wolfgang
中科院分区：
文献类型：
--
作者：
Mueller-Tasch, Thomas;Frankenstein, Lutz;Herzog, Wolfgang
目的：我们的目的是评估慢性心力衰竭（CHF）门诊患者惊恐障碍的患病率、其对生活质量（QoL）的影响以及是否存在其他焦虑和抑郁共病障碍。方法：在一项横断面研究中，使用患者健康问卷，依据《精神障碍诊断与统计手册》第四版诊断标准，对年龄≥18岁且纽约心脏协会（NYHA）心功能分级为I - IV级的CHF患者进行焦虑和抑郁障碍诊断。使用36项简短健康调查问卷（SF - 36）评估与健康相关的生活质量。结果：在258名参与研究的患者中，24名（9.3%）符合惊恐障碍诊断标准。其中7名（29.2%）被诊断患有共病焦虑障碍，11名（47.3%）被诊断患有共病抑郁障碍，5名（20.8%）被诊断患有其他焦虑障碍和任何一种抑郁障碍。女性[比值比（OR）=3.1；95%置信区间（95%CI）=1.2 - 7.8；P = 0.02]和较低的教育水平（OR = 0.3；95%CI = 0.1 - 0.9；P = 0.04）与惊恐障碍的存在相关。与无惊恐障碍的患者相比，惊恐障碍患者在SF - 36的所有子量表上生活质量都受到更显著的限制，即使在控制年龄、性别和NYHA心功能分级后也是如此（P = 0.05至……
Objective: Our objective was to assess the prevalence of panic disorder, its influence on quality of life (QoL), and the presence of further anxiety and depressive comorbid disorders in outpatients with chronic heart failure (CHF). Methods: In a cross-sectional study, anxiety and depressive disorders were diagnosed according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition diagnostic criteria in patients with CHF who were aged >= 18 years and had New York Heart Association (NYHA) Functional Classes I-IV, using the Patient Health Questionnaire. Health-related QoL was evaluated using the Short-Form 36 Health Survey (SF-36). Results: Of the 258 participating patients, 24 (9.3%) fulfilled diagnostic criteria for panic disorder. Seven of these (29.2%) were diagnosed with comorbid anxiety disorders, 11 (47.3%) were diagnosed with comorbid depressive disorder, and 5 (20.8%) were diagnosed with other anxiety disorders and any depressive disorder. Female gender [odds ratio (OR)=3.1; 95% confidence interval (95% CI)=1.2-7.8; P=.02] and a lower level of education (OR=0.3; 95% CI=0.1-0.9; P=.04) were associated with the presence of panic disorder. In patients with panic disorder, QoL was significantly more restricted on all subscales of the SF-36 as compared to those without panic disorder, even when age, gender, and NYHA functional class were controlled for (P=.05 to