Intracranial self-stimulation in 3-day-old rat pups.
Intracranial self-stimulation in 3-day-old rat pups.
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3天大的幼鼠颅内自我刺激。
DOI：
10.1126/science.6975999
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
Blass,EM
中科院分区：
文献类型：
--
作者：
Moran,TH;Lew,MF;Blass,EM
三天大的大鼠幼崽与电极直接在内侧前脑束水平的外侧下丘脑区进行训练，推动桨接受脑电刺激。接受刺激的幼犬比对照组的幼犬反应更频繁，并且还学会了一项两种选择的空间辨别任务，该任务以大脑刺激作为奖励。实验表明，在该地区的内侧前脑束的神经基板参与了中央调解的强化在大鼠幼崽。
Three-day-old rat pups with electrodes directed at the medial forebrain bundle at the level of the lateral hypothalamic area were trained to push a paddle to receive electrical brain stimulation. Pups receiving stimulation that was contingent on lifting the paddle responded more frequently than did control pups and also learned a two-choice spatial discrimination task that was rewarded with brain stimulation. The experiments indicate that a neural substrate in the area of the medial forebrain bundle is involved in the central mediation of reinforcement in the rat pup.