SUPRAMAMMILLARY CELL FIRING AND HIPPOCAMPAL RHYTHMICAL SLOW ACTIVITY

SUPRAMAMMILLARY CELL FIRING AND HIPPOCAMPAL RHYTHMICAL SLOW ACTIVITY
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DOI:
10.1097/00001756-199111000-00023
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发表时间:
1991-11-01
期刊:
影响因子:
1.7
通讯作者:
MCNAUGHTON, N
MCNAUGHTON, N
中科院分区:
医学4区
文献类型:
--
作者:
KIRK, IJ;MCNAUGHTON, N

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从乌拉坦麻醉大鼠的乳头体上区域记录细胞外多单位活动,同时记录海马EEG。乳头体上区细胞放电的模式被发现是有节奏的,并与并发海马节律性慢活动(RSA)的阶段。隔室注射普鲁卡因(20%,1-5 μ l),可以消除海马RSA,但不能消除乳头体上细胞放电的节律性。这些数据表明,海马RSA的频率可能是在乳头体上区,而不是在内侧隔,如以前所假设的。
EXTRACELLULAR multi-unit activity was recorded from sites in the supramammillary area of urethane anaesthetized rats, while simultaneously recording the hippocampal EEG. The pattern of supramammillary area cell discharge was found to be rhythmic and in phase with concurrent hippocampal rhythmical slow activity (RSA). Septal application of procaine (20%, 1-5-mu-l), that abolished hippocampal RSA, did not abolish the rhythmicity of supramammillary cell firing. These, data suggest that the frequency of hippocampal RSA may be determined in the supramammillary area rather than in the medial septum as has previously been supposed.