A permanent prosthesis for converting in situ muscle contractions into hydraulic power for cardiac assist.
A permanent prosthesis for converting in situ muscle contractions into hydraulic power for cardiac assist.
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一种永久性假体，用于将原位肌肉收缩转化为液压动力以辅助心脏。
DOI：
10.1152/jappl.1997.82.5.1704
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发表时间：
1997
影响因子：
3.3
通讯作者：
James A. Magovern
中科院分区：
文献类型：
--
作者：
D. Trumble;James A. Magovern
利用肌肉力量支持循环的关键在于开发一种实用的方案，通过该方案可以收集收缩能量并有效地将其输送到血液中。这项工作描述了一个原型肌肉能量转换器（MEC）的初步体外测试，旨在将原位肌肉收缩的力量转化为水力形式。MEC类似于一个简单的活塞泵，设计用于植入背阔肌肱骨止点下方。台架试验进行了测量组件功能和表征设备性能在各种液压载荷。在模拟肌肉拉扯条件下，MEC的能量传递能力为170 mJ/冲程，同时运行在峰值效率（即> 98%的输入功率转化为液压能量和预载功）。由于金属波纹管弯曲，平均产生压力从23 N/cm2增加到36 N/cm2，传递效率从96%下降到38%。这些结果表明，通过该机构可以有效地将大量的收缩能转化为水力。
The key to utilizing muscle power for circulatory support lies with the development of a practical scheme by which contractile energy may be collected and efficiently delivered to the bloodstream. This work describes initial in vitro testing of a prototype muscle energy converter (MEC) designed to transform the power of in situ muscle contractions into hydraulic form. The MEC resembles a simple piston pump and is designed for implant beneath the humeral insertion of the latissimus dorsi muscle. Bench tests were conducted to measure component function and to characterize device performance under various hydraulic loads. Under simulated muscle-pull conditions, MEC energy transfer capacity was found to be 170 mJ/stroke while operating at peak efficiencies (i.e., > 98% of input power converted into hydraulic energy and preload work). Transfer efficiencies dropped from 96 to 38% as mean generated pressures increased from 23 to 36 N/cm2 due to metal bellows flexion. These results demonstrate that a significant amount of contractile energy can be efficiently transformed to hydraulic power via this mechanism.
骨骼肌心室循环长期：一百九十一至八百三十六天。
DOI：
--
发表时间：
1992
期刊：
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
影响因子：
--
作者：
Mocek,FW;Anderson,DR;Pochettino,A;Hammond,RL;Spanta,A;Ruggiero,R;Thomas,GA;Lu,H;Fietsam,R;Nakajima,H
通讯作者：
Nakajima,H
1993年心室辅助和全人工心脏装置投入临床使用。
DOI：
--
发表时间：
1993
期刊：
ASAIO journal (American Society for Artificial Internal Organs : 1992)
影响因子：
--
作者：
Rowles,JR;Mortimer,BJ;Olsen,DB
通讯作者：
Olsen,DB