Continuous parathyroid hormone induces cortical porosity in the rat: Effects on bone turnover and mechanical properties

Continuous parathyroid hormone induces cortical porosity in the rat: Effects on bone turnover and mechanical properties
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DOI:
10.1359/jbmr.040404
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发表时间:
2004-07-01
影响因子:
6.2
通讯作者:
Turner, RT
Turner, RT
中科院分区:
医学1区
文献类型:
--
作者:
Lotinun, S;Evans, GL;Turner, RT

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我们研究了持续PTH对皮质骨和机械性能的时间过程影响。PTH增加皮质骨转换,诱导皮质内孔隙,对骨强度无有害影响。撤回PTH增加了最大失效扭矩和刚度,而吸收的能量没有变化。
We examined the time course effects of continuous PTH on cortical bone and mechanical properties. PTH increased cortical bone turnover and induced intracortical porosity with no deleterious effect on bone strength. Withdrawal of PTH increased maximum torque to failure and stiffness with no change in energy absorbed.