PAIN AND OTHER SYMPTOMS AFTER DIFFERENT TREATMENT MODALITIES OF BREAST-CANCER
PAIN AND OTHER SYMPTOMS AFTER DIFFERENT TREATMENT MODALITIES OF BREAST-CANCER
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DOI：
10.1093/oxfordjournals.annonc.a059215
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发表时间：
1995-05-01
影响因子：
50.5
通讯作者：
KALSO, E
中科院分区：
文献类型：
--
作者：
TASMUTH, T;VONSMITTEN, K;KALSO, E
目的：本研究的目的是分析的危险因素，易患妇女的慢性症状相关的治疗乳腺cancer.Patients和方法：问卷调查发送到569名妇女谁经历了改良根治性乳房切除术与腋窝疏散（MRM）或乳房切除术与腋窝疏散（BCT）。慢性疼痛轻微影响约50%患者的日常生活，中度或更多影响约25%患者的日常生活。在乳房瘢痕（BS）和同侧手臂（IA）中，BCT后报告的疼痛明显多于MRM后。慢性疼痛患者明显更年轻，原发肿瘤更大。术后并发症增加了IA慢性疼痛的发生率。接受过放疗和化疗的患者报告的IA疼痛发生率最高。事实上，疼痛（IA）的发病率有显着的相关性的发生异常感觉，水肿，奇怪的感觉和肌无力可能是一个指标的神经injure.Conclusions：慢性疼痛是更常见的保乳手术后比根治性手术。手术并发症和术后放疗和化疗增加了慢性疼痛和其他症状的风险。为了尽量减少慢性治疗相关症状，可能需要修改治疗方案并预防术后并发症。
Purpose: The aim of this study was to analyse the risk factors that predispose women to chronic symptoms related to the treatment of breast cancer.Patients and methods: A questionnaire was sent to 569 women who had undergone modified radical mastectomies with axillary evacuation (MRM) or breast resection with axillary evacuation (BCT).Results: Pain, paraesthesias and strange sensations were reported by half of the patients. The chronic pain slightly affected the daily lives of about 50% of the patients and moderately or more the daily lives of about 25% of the patients. Pain was reported significantly more often after BCT than after MRM both in the breast scar (BS) and in the ipsilateral arm (IA). The patients with chronic pain were significantly younger and had larger primary tumours. Postoperative complications increased the incidence of chronic pain in the IA. The highest incidence of pain in the IA was reported by patients who had had both radio- and chemotherapy. The fact that the incidence of pain (IA) had a significant correlation with the incidence of paraesthesias, oedema, strange sensations and muscle weakness may be an indication of nerve injury.Conclusions: Chronic pain was more common after breast-conserving surgery than after radical surgery. Surgical complications and postoperative radiotherapy and chemotherapy increased the risk of chronic pain and other symptoms. Modifications in the treatment protocol and preclusion of postoperative complications may be necessary in order to minimize chronic treatment-related symptoms.