MYOINOSITOL CONTENT OF COMMON FOODS - DEVELOPMENT OF A HIGH-MYO-INOSITOL DIET
MYOINOSITOL CONTENT OF COMMON FOODS - DEVELOPMENT OF A HIGH-MYO-INOSITOL DIET
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DOI：
10.1093/ajcn/33.9.1954
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发表时间：
1980-01-01
影响因子：
7.1
通讯作者：
DARNELL, B
中科院分区：
文献类型：
--
作者：
CLEMENTS, RS;DARNELL, B
几乎没有关于膳食成分中肌醇含量的信息; 487种食物中这种物质的含量是用气相色谱法测量的。水果、豆类、谷物和坚果中的肌醇含量最多。新鲜蔬菜和水果比冷冻、罐装或无盐产品含有更多的肌醇。饮食中含有不同的，但已知量的肌醇被开发出来。这种饮食可提供的肌醇摄入量范围为225-1500 mg/天/1800 kcal;在此范围内，该材料的计算量和测量量之间的一致性极佳（r = 0.98）。据推测，肌醇代谢异常在与糖尿病和慢性肾功能衰竭相关的多发性神经病变的发病机制中发挥作用;这些神经病变的自然史可能通过改变这些疾病患者摄入的膳食肌醇量而改变。
Virtually no information is available concerning the myo-inositol content of dietary constituents; the amount of this material present in 487 foods was measured by GLC. The greatest amounts of myo-inositol were present in fruits, beans, grains and nuts. Fresh vegetables and fruits contained more myo-inositol than did frozen, canned or salt-free products. Diets that contained varying, but known amounts of myo-inositol were developed. The myo-inositol intake that could be provided by such diets ranged from 225-1500 mg/day per 1800 kcal; within this range the agreement between the calculated and measured amounts of this material was excellent (r = 0.98). Abnormalities in the metabolism of myo-inositol were speculated to play a role in the pathogenesis of the polyneuropaghies associated with diabetes mellitus and chronic renal failure; the natural history of these neuropathies may be altered by modifying the amount of dietary myo-inositol ingested by patients with these diseases.