14_MCA-based Embryology and Embryo Imaging.
14_MCA-based Embryology and Embryo Imaging.
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14_基于 MCA 的胚胎学和胚胎成像。
DOI：
10.1007/978-981-16-4325-5_14
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Yamada S.
中科院分区：
文献类型：
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作者：
Nakano S;Kodama R;Yamaguchi Y;Takakuwa T;Yamada S.
人类胚胎学的研究有着悠久的历史，因为它在19世纪首次建立的人类胚胎收集中得到了发展。第一个建立的大型人类胚胎收集是卡内基收集，随后是其他几个主要的收集。在根据发育胚胎的形态学特征定义卡内基发育阶段后，研究人员进行了形态学测量和分析，以有效地利用储存的标本发现新的见解。目前，使用无损方法进行分析已被优先考虑，并采用新颖的成像技术来保存标本，并促进了3D成像模式的使用。对组织和器官进行三维可视化有助于理解和描述体内复杂的形态变化。3D成像模式的使用始于20世纪，使用组织学切片进行重建，现在，3D图像数据集也被使用。本章描述了如何收集，以提供对人类胚胎发育的新见解，以及用于形态分析的新型3D成像技术及其应用方法的细节。
The study of human embryology has a long history owing to its development in the human embryo collections that were first established in the nineteenth century. The first established large collection of human embryos was the Carnegie Collection, followed by several other major collections. After the Carnegie stages of development were defined based on morphological features of developing embryos, researchers have conducted morphological measurements and analyses to discover new insights using the stored specimens efficiently. At present, conducting analysis using nondestructive methods has been prioritized, and novel imaging techniques are adopted to preserve the specimens and have promoted the use of 3D imaging modalities. Visualizing tissues and organs in three dimensions has helped understand and characterize complex morphogenic changes in the body. The use of 3D imaging modalities started in the twentieth century using the histological sections for reconstruction, and now, 3D image datasets are also used. This chapter describes how the collections have been made, to provide new insights into human embryonic development, along with details of novel 3D imaging techniques for morphological analyses and their methods of application.