HEIGHT AND WEIGHT IN RELATION TO BREAST-CANCER MORBIDITY AND MORTALITY - A PROSPECTIVE-STUDY OF 570,000 WOMEN IN NORWAY

HEIGHT AND WEIGHT IN RELATION TO BREAST-CANCER MORBIDITY AND MORTALITY - A PROSPECTIVE-STUDY OF 570,000 WOMEN IN NORWAY
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DOI:
10.1002/ijc.2910440105
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发表时间:
1989-07-15
影响因子:
6.4
通讯作者:
TRETLI, S
TRETLI, S
中科院分区:
医学1区
文献类型:
--
作者:
TRETLI, S

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测量了570 000名30-69岁挪威妇女的身高和体重,然后对受试者进行了6-18年的乳腺癌发病率和死亡率随访。他们被安排在5岁的年龄组。在所有年龄组中,最高的妇女被发现有最高的发病率和死亡率风险。超重是所有年龄组乳腺癌死亡率的一个危险因素,但在发病率方面,它只是绝经后年龄组的一个危险因素。它似乎可以预防绝经前年龄组的乳腺癌。I期和II-IV期随访终点分别显示与超重的负相关和正相关。这不太可能完全解释为苗条女性早期发现癌症。
The height and weight of 570,000 Norwegian women, aged 30-69 years, were measured and the subjects were then followed up for 6-18 years with regard to breast cancer morbidity and mortality. They were arranged in 5-year age-groups. In all age-groups the tallest women were found to have the highest risk for both morbidity and mortality. Overweight was a risk factor for breast cancer mortality in all age-groups, but it was a risk factor only in the post-menopausal age-groups in the case of morbidity. It appeared to protect against breast cancer in the pre-menopausal age-group. stages I and II-IV follow-up endpoints show negative and positive associations, respectively, with overweight. It is not likely that this can be fully explained by earlier detection of cancer among slim women.