The first example of silica nanoshell synthesis on vesicles of a cationic glycerolipid-potential antitumor drug

The first example of silica nanoshell synthesis on vesicles of a cationic glycerolipid-potential antitumor drug
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DOI:
10.1134/s1061933x16020034
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发表时间:
2016-03-01
期刊:
影响因子:
1.1
通讯作者:
Rudoy, V. M.
Rudoy, V. M.
中科院分区:
化学4区
文献类型:
--
作者:
Dement'eva, O. V.;Roumyantseva, T. B.;Rudoy, V. M.

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首次显示二氧化硅纳米壳可以在外消旋-N-{4-2-乙氧基-3-十八烷氧基丙-1-基)氧羰基]丁基}-N '-甲基咪唑鎓碘化物的囊泡上制备,所述外消旋-N-{4-2-乙氧基-3-十八烷氧基丙-1-基)氧羰基]丁基}-N'-甲基咪唑鎓碘化物是具有显著抗肿瘤作用的阳离子甘油脂质。
It has, for the first time, been shown that silica nanoshells may be prepared on vesicles of rac-N-{4-2-ethoxy-3-octadecyloxyprop-1-yl)oxycarbonyl]butyl}-N'-methylimidazolium iodide, which is a cationic glycerolipid with a pronounced antitumor effect.