Recent trends in cerebral palsy survival. Part I: period and cohort effects
Recent trends in cerebral palsy survival. Part I: period and cohort effects
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DOI：
10.1111/dmcn.12520
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发表时间：
2014-11-01
影响因子：
3.8
通讯作者：
Wu, Yvonne W.
中科院分区：
文献类型：
--
作者：
Brooks, Jordan C.;Strauss, David J.;Wu, Yvonne W.
AimTo确定是否改善生存的趋势在加州在20世纪80年代和90年代的个人与脑性瘫痪（CP）在最近的decade.MethodIn一项观察性队列研究中，我们评估了个人与CP，年龄在4岁及以上，谁是客户的加州部的发展服务。医疗诊断，功能障碍，和特殊的医疗保健需求进行了评估与客户发展评估报告之间的1983年和2010年。采用KaplanMeier曲线和考克斯回归分析出生队列生存率的趋势。日历年期间的影响进行了分析Poisson regression.ResultsA共51923人CP（28789男性[55%]，23134女性[45%];平均年龄14年11个月，SD 14年1个月，范围4年0个月至96年10个月）集体贡献了662268年的后续行动。有7 690人死亡，总死亡率为每年每1 000人11.6人。在没有严重残疾的4岁儿童中，没有观察到出生队列对生存率的显著影响。相比之下，最近几年出生的未抬头俯卧位的儿童的死亡率显著较低（考克斯风险比0.971，p
AimTo determine whether the trend of improved survival among individuals with cerebral palsy (CP) in California during the 1980s and 1990s has continued during the most recent decade.MethodIn an observational cohort study we evaluated individuals with CP, aged 4years and older, who were clients of the California Department of Developmental Services. Medical diagnoses, functional disabilities, and special health care requirements were assessed with Client Development Evaluation Reports made between 1983 and 2010. Trends in birth cohort survival were analyzed with KaplanMeier curves and Cox regression. Calendar year period effects were analyzed with Poisson regression.ResultsA total of 51923 persons with CP (28789 males [55%], 23134 females [45%]; mean age 14y 11mo, SD 14y 1mo, range 4y 0mo to 96y 10mo) collectively contributed 662268years of follow-up. There were 7690 deaths for an overall mortality rate of 11.6 per 1000 persons per year. No significant birth cohort effects on survival were observed in 4-year-olds who had no severe disabilities. By contrast, children who did not lift their heads in prone position who were born in more recent years had significantly lower mortality rates (Cox hazard ratio 0.971, p