Long-term reliability of AAI mode pacing in patients with sinus node dysfunction and low Wenckebach block rate
Long-term reliability of AAI mode pacing in patients with sinus node dysfunction and low Wenckebach block rate
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DOI：
10.1093/europace/eum290
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发表时间：
2008-02-01
期刊：
影响因子：
6.1
通讯作者：
Hisatome, Ichiro
中科院分区：
文献类型：
--
作者：
Adachi, Masamitsu;Igawa, Osamu;Hisatome, Ichiro
目的比较AAI起搏时窦房结功能障碍患者与文氏阻滞率(WBR)较高的患者发生房室传导障碍的危险性。将患者分为两组：L组为WBR100~129/min组，H组为WBR&Gt；=130/min组。所有患者在植入AAI起搏器后每隔3-6个月随访一次。L组35例，H组67例，随访90+/-44个月。6名患者死于非心脏原因，5名患者需要新的心房。随访期因导线失效植入导线。有症状性心动过缓需要植入新的脑室导线的患者有4例(年发病率为0.5%)。L组发生房室传导阻滞2例(年发生率0.7%)。H组有2例患者发生心动过缓房颤(年发生率为0.4%)。卡普兰-迈耶分析显示两组间无显著差异(P=0.2983)。结论这些结果提示，即使WBR100~129/min的患者发生房室传导障碍的长期风险也是两倍的。
Aims To compare the risk of atrioventricular (AV) conduction disturbance between patients with sinus node dysfunction on AAI pacing who had a tow or high Wenckebach block rate (WBR).Methods and results Patients with sinus node dysfunction and normal AV conduction those underwent an electrophysiological study were studied. The patients were classified into two groups: Group L was with the patients with a WBR of 100 to 129 per minute and Group H was with the patients with a WBR >= 130 per minute. All patients followed up every 3-6 months after an AAI pacemaker implantation. A total of 102 patients, including 35 Group L and 67 Group H, were followed for 90 +/- 44 months. Six patients died from non-cardiac cause and five patients required a new atrial. lead implantation due to lead failure during follow-up. Symptomatic bradycardia requiring a new ventricular Lead implantation developed in four patients (annual incidence 0.5%). In Group L, two patients developed AV block (annual incidence 0.7%). In Group H, two patients developed bradycardic atrial fibrillation (annual incidence 0.4%). Kaplan-Meier analysis revealed no significant difference between the two groups (P = 0.2983).Conclusion These results suggest that a tong-term risk of developing AV conduction disturbance is tow even in patients with a WBR of 100 to 129 per minute.