MENTAL ILLNESS IN BIOLOGICAL AND ADOPTIVE FAMILIES OF ADOPTED SCHIZOPHRENICS
MENTAL ILLNESS IN BIOLOGICAL AND ADOPTIVE FAMILIES OF ADOPTED SCHIZOPHRENICS
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DOI：
10.1176/ajp.128.3.302
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发表时间：
1971-01-01
影响因子：
17.7
通讯作者：
SCHULSINGER, F
中科院分区：
文献类型：
--
作者：
KETY, SS;ROSENTHAL, D;SCHULSINGER, F
收养已被用作区分精神分裂症在家庭成员之间传播的遗传因素和环境因素的一种手段。在此报告的研究中，在收养的精神分裂症患者的亲生亲属中发现精神分裂症相关疾病的患病率显着高于平常，但在其收养的亲属中则不然。这些发现支持精神分裂症的易感性通过遗传传播，但也暗示临床精神分裂症的发展需要非遗传的环境因素。
Adoption has been used as a means of separating genetic and environmental factors in the transmission of schizophrenia among family members. In the study reported here, a significantly higher than usual prevalence of schizophrenia-related illness was found among the biological relatives of adopted schizophrenics, but not among their adoptive relatives. The findings support a genetic transmission of vulnerability to schizophrenia, but also imply the requirement of nongenetic, environmental factors for the development of clinical schizophrenic illness.