Tubal pregnancy associated with additional conception in a contralateral tube
Tubal pregnancy associated with additional conception in a contralateral tube
复制标题
与对侧输卵管额外受孕相关的输卵管妊娠
DOI：
10.1111/jog.12744
复制
发表时间：
2015
期刊：
影响因子：
--
通讯作者：
and Shozu M
中科院分区：
文献类型：
--
作者：
Ishikawa H;Kiyokawa T;Okayama J;Usui H;and Shozu M
位置不明的妊娠被定义为妊娠试验阳性但子宫内膜空洞，通常发展为显性宫内或宫外孕。然而，位置不明的持续性妊娠的病理生理机制尚不清楚，其中包括持续低血清人绒毛膜促性腺激素，但没有任何可见的植入部位。我们报告一例左侧输卵管妊娠合并对侧输卵管妊娠。一名40岁的未孕妇女在体外受精后进行了两次胚胎移植，疑似左侧输卵管妊娠。对双侧输卵管积水施行腹腔镜双侧输卵管切除术。另一个概念的产品是在正确的试管中鉴定出来的。用切除标本的基因组DNA进行的短串联重复分析表明了两个不同起源的概念。显微镜下发现的异常妊娠可能是不明部位持续性妊娠的一种发病机制。输卵管积水的对侧输卵管切除术是预防持续隐匿性妊娠的一种选择。
Pregnancy of unknown location is defined as empty endometrial cavity despite positive pregnancy test, and often develops as overt intrauterine or ectopic pregnancy. The pathophysiology of persistent pregnancy of unknown location, however, which involves continuous low serum human chorionic gonadotropin without any visible implantation site, is unknown. We report a case of left tubal pregnancy associated with additional conception in the contralateral tube. Left tubal pregnancy was suspected in a 40‐year‐old nulligravid woman after two embryo transfers followingin vitrofertilization. Laparoscopic bilateral salpingectomy was performed for bilateral hydrosalpinx. Products from an additional conception were identified in the right tube. Short tandem repeat analysis using genomic DNA from resected specimens indicated two conceptions of different origin. The extra conception identified on microscopy may indicate one pathogenesis of persistent pregnancy of unknown location. Salpingectomy of the contralateral tube with hydrosalpinx is an option to prevent persistent occult pregnancy.