Genotypes of multidrug-resistant Salmonella enterica serotype typhimurium from two regions of Kenya
Genotypes of multidrug-resistant Salmonella enterica serotype typhimurium from two regions of Kenya
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DOI：
10.1111/j.1574-695x.2000.tb01498.x
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发表时间：
2000-09-01
影响因子：
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通讯作者：
Hart, CA
中科院分区：
文献类型：
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作者：
Kariuki, S;Oundo, JO;Hart, CA
已采用噬菌体分型以及对XbaI消化的染色体DNA进行脉冲场凝胶电泳相结合的方法，对1994 - 1997年期间从内罗毕（64株）和基利菲（40株）收集的多重耐药性肠炎沙门氏菌血清型鼠伤寒的流行病学关系进行了研究。来自内罗毕的菌株属于11种确定的噬菌体类型（DTs），包含8种不同的脉冲场凝胶电泳图谱模式。相比之下，来自基利菲的菌株主要是DT56（占60%），且都属于一种脉冲场凝胶电泳图谱模式。其余的菌株不符合可识别的噬菌体类型。我们得出结论，内罗毕的多重耐药性鼠伤寒沙门氏菌感染是由多种菌株引起的，而来自基利菲的感染很可能是由单一克隆引起的小规模流行所致。（C）2000年欧洲微生物学会联合会。由爱思唯尔科学出版社出版。保留所有权利。
A combination of phage typing and pulsed-field gel electrophoresis of XbaI-digested chromosomal DNA has been used to study the epidemiological relationships of multidrug-resistant Salmonella enterica serotype typhimurium from Nairobi (64 isolates) and Kilifi (40 isolates) collected over the period 1994-1997. Isolates from Nairobi belonged to 11 definitive phage types (DTs) encompassing eight different PFGE patterns. In contrast, isolates from Kilifi were mainly DT 56 (60%) and all fell into a single PFGE pattern. The remaining isolates did not conform to a recognisable phage type. We conclude that multidrug-resistant S. typhimurium infections from Nairobi were caused by multiple strains while those From Kilifi were likely to be from a microepidemic caused by a single clone, (C) 2000 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.