Risk Factors for Low Birth Weight in an Indian Urban Setting
Risk Factors for Low Birth Weight in an Indian Urban Setting
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DOI：
10.1177/1010539511431486
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发表时间：
2014-09
影响因子：
2.5
通讯作者：
P. Negandhi;H. Negandhi;S. Zodpey;S. Ughade;J. R. Biranjan
中科院分区：
文献类型：
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作者：
P. Negandhi;H. Negandhi;S. Zodpey;S. Ughade;J. R. Biranjan
本研究采用嵌套病例对照设计，探讨了印度城市环境中低出生体重（LBW）的危险因素。研究人员从384名在产前诊所就诊的孕妇那里收集了潜在风险因素的信息，并对她们进行了随访，直到分娩。根据出生体重，这些妇女的婴儿被分为病例组和对照组。各危险因素与出生体重之间的双变量分析显示，与产妇年龄≤20岁、妊娠前三个月后产前门诊登记、产前就诊≤5次、以及卡路里和蛋白质推荐膳食摄入量<80%存在未调整的显著关联（P < 0.05）。多元logistic回归分析显示，卡路里摄入量<80% RDA (P < 0.048)，低锌摄入量（P < 0.001）和产前检查≤5次（P < 0.001）与调整后的显著相关。这项研究强调了及时和定期产前检查以及摄入适量卡路里的持续重要性。锌作为LBW的危险因素的作用值得进一步研究。
This study explores the risk factors for low birth weight (LBW) in an urban Indian setting by using a nested case-control design. Information on potential risk factors was sought from 384 pregnant women attending an antenatal clinic, and they were followed until birth. Based on birth weight, the babies of these women were categorized as cases or controls. Bivariate analyses between each risk factor and birth weight showed an unadjusted significant association (P < .05) for maternal age ≤20 years, antenatal clinic registration after the first trimester, ≤5 antenatal visits, and <80% of the recommended dietary allowance (RDA) for calories and proteins. Multiple logistic regression analysis showed an adjusted significant association for calorie intake <80% RDA (P < .048), low zinc intake (P < .001), and ≤5 antenatal visits (P < .001). This study emphasizes the continuing importance of timely and regular antenatal visits and intake of appropriate amount of calories. The role of zinc as a risk factor for LBW warrants further research.