Cognition, mood, and physiological concentrations of sex hormones in the early and late postmenopause
Cognition, mood, and physiological concentrations of sex hormones in the early and late postmenopause
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DOI：
10.1073/pnas.1312353110
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发表时间：
2013-12-10
影响因子：
11.1
通讯作者：
Mack, Wendy J.
中科院分区：
文献类型：
--
作者：
Henderson, Victor W.;St John, Jan A.;Mack, Wendy J.
绝经后激素环境的变化可能会影响与认知、认知老化和情绪有关的神经过程，但研究结果并不一致。特别是，雌二醇的认知效应可能会随着绝经后的时间而变化，但这种预测尚未直接使用血清激素浓度进行评估。我们研究了643名未使用激素治疗的健康绝经后妇女，
Variations in the hormonal milieu after menopause may influence neural processes concerned with cognition, cognitive aging, and mood, but findings are inconsistent. In particular, cognitive effects of estradiol may vary with time since menopause, but this prediction has not been assessed directly using serum hormone concentrations. We studied 643 healthy postmenopausal women not using hormone therapy who were recruited into early (