Changes in the Distribution of Periodontal Nerve Fibers during Dentition Transition in the Cat
Changes in the Distribution of Periodontal Nerve Fibers during Dentition Transition in the Cat
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DOI：
10.1371/journal.pone.0129826
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发表时间：
2015-06-17
期刊：
影响因子：
3.7
通讯作者：
Wakisaka, Satoshi
中科院分区：
文献类型：
--
作者：
Miki, Koji;Honma, Shiho;Wakisaka, Satoshi
牙周膜有丰富的感觉神经供应，其来源于三叉神经节和三叉神经中脑核。虽然各种类型的机械感受器已被报道在牙周膜，Ruffini结束是一个必不可少的。乳牙牙周神经纤维的分布与恒牙牙周神经纤维的分布是否相同尚不清楚。此外，牙周神经纤维的分布在形态学上的变化，在乳牙的吸收和连续恒牙的萌出在双齿动物还没有详细的报告。因此，在这项研究中，我们检查了猫在牙列变化期间牙周神经纤维分布的变化（即，乳牙、混合牙和恒牙）通过蛋白质基因产物的免疫组织化学9.5.乳牙期牙周神经纤维主要集中在根尖部，而在牙周膜内分布稀疏。替牙期乳磨牙牙周神经纤维在吸收过程中呈现退行性改变。恒牙期，恒牙前磨牙的牙周神经纤维数量增多。与恒前磨牙相似，恒磨牙的牙周神经纤维数量增多，且密集于根尖部。结果表明，乳牙期牙周神经纤维的分布与恒牙期基本一致，但乳牙期牙周神经纤维的数量较少。乳牙期牙周神经纤维的稀疏分布与临床证据一致，即儿童对牙齿刺激的敏感性低于成人。
The periodontal ligament has a rich sensory nerve supply which originates from the trigeminal ganglion and trigeminal mesencephalic nucleus. Although various types of mechanoreceptors have been reported in the periodontal ligament, the Ruffini ending is an essential one. It is unknown whether the distribution of periodontal nerve fibers in deciduous teeth is identical to that in permanent teeth or not. Moreover, morphological changes in the distribution of periodontal nerve fibers during resorption of deciduous teeth and eruption of successional permanent teeth in diphyodont animals have not been reported in detail. Therefore, in this study, we examined changes in the distribution of periodontal nerve fibers in the cat during changes in dentition (i.e., deciduous, mixed and permanent dentition) by immunohistochemistry of protein gene product 9.5. During deciduous dentition, periodontal nerve fibers were concentrated at the apical portion, and sparsely distributed in the periodontal ligament of deciduous molars. During mixed dentition, the periodontal nerve fibers of deciduous molars showed degenerative profiles during resorption. In permanent dentition, the periodontal nerve fibers of permanent premolars, the successors of deciduous molars, increased in number. Similar to permanent premolars, the periodontal nerve fibers of permanent molars, having no predecessors, increased in number, and were densely present in the apical portion. The present results indicate that the distribution of periodontal nerve fibers in deciduous dentition is almost identical to that in permanent dentition although the number of periodontal nerve fibers in deciduous dentition was low. The sparse distribution of periodontal nerve fibers in deciduous dentition agrees with clinical evidence that children are less sensitive to tooth stimulation than adults.