UK Scleroderma Study Group (UKSSG) guidelines on the diagnosis and management of scleroderma renal crisis.
UK Scleroderma Study Group (UKSSG) guidelines on the diagnosis and management of scleroderma renal crisis.
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发表时间：
2016-10
影响因子：
3.7
通讯作者：
B. Lynch;Edward P. Stern;V. Ong;M. Harber;Á. Burns;C. Denton
中科院分区：
文献类型：
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作者：
B. Lynch;Edward P. Stern;V. Ong;M. Harber;Á. Burns;C. Denton
英国硬皮病研究小组根据现有的最佳证据和临床经验，制定了硬皮病肾脏危象(SRC)的诊断和治疗指南。SRC的特点是急性发作严重高血压和急性肾脏损伤。目前减少相关发病率和死亡率的策略包括识别高危患者以帮助早期诊断。无论患者是否需要肾脏替代治疗，血管紧张素转换酶抑制剂治疗都应该是终生的。SRC患者可能在危象发生后3年内恢复肾功能，通常在12至18个月内恢复。
The UK Scleroderma Study Group developed guidelines on the diagnosis and management of scleroderma renal crisis (SRC) based on best available evidence and clinical experience. SRC is characterised by the acute onset of severe hypertension and acute kidney injury. Current strategies to reduce the associated morbidity and mortality include identifying at risk patients to aid early diagnosis. ACE inhibitor therapy should be lifelong in all patients, regardless of whether they require renal replacement therapy. Patients with SRC may recover renal function up to 3 years after the crisis, most often within 12 to 18 months.