Albumin-corrected Total/Ionized Calcium Ratio is not Superior to Total/Ionized Calcium Ratio as an Indicator of Citrate Accumulation
Albumin-corrected Total/Ionized Calcium Ratio is not Superior to Total/Ionized Calcium Ratio as an Indicator of Citrate Accumulation
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作为柠檬酸盐积累的指标，白蛋白校正的总钙/离子钙比并不优于总钙/离子钙比
DOI：
10.5301/ijao.5000621
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发表时间：
2017-07
期刊：
影响因子：
--
通讯作者：
Feng Ding
中科院分区：
文献类型：
--
作者：
Yin Zheng;Feng Zhuang;Qiuyu Zhu;Shuai Ma;Yao Xu;Jianxin Lu;Guihua Hao;Yong Gu;Chuanming Hao;Mingli Zhu;Feng Ding
背景：总钙/离子钙比值一直被用作柠檬酸盐抗凝过程中血浆柠檬酸盐浓度升高的间接指标。然而，这些数据是在未对总钙进行白蛋白校正的情况下获得的。在此，我们研究了……
Background Total/ionized calcium ratio has been used as an indirect index of increased plasma citrate concentration during citrate anticoagulation. However, they were obtained without any adjustment of total calcium for albumin. Herein, we investigated whether the albumin-corrected total/ionized calcium ratio performed better than total/ionized calcium ratio. Methods 20 critically ill patients were treated with continuous venovenous hemofiltration (CVVH) using citrate anticoagulation. The systemic total, ionized calcium and albumin levels were dynamically measured, and correlations between different calcium parameters and plasma citrate levels were analyzed. Results The highest correlation was found between plasma citrate level and total/ionized calcium ratio at the third hour (R = 0.88, p<0.001). The albumin-corrected total/ionized calcium ratio was not superior to total/ionized calcium ratio. Conclusions The total/ionized calcium ratio at the third hour after the start of citrate-CVVH is an early and simple indicator to reflect increased plasma citrate level. Adjustment of systemic total calcium for serum albumin is not necessary.
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影响因子：
6.1
作者：
Mariano, Filippo;Morselli, Maurizio;Triolo, Giorgio
通讯作者：
Triolo, Giorgio
影响因子：
8.8
作者：
Meier-Kriesche, HU;Gitomer, J;DuBose, T
通讯作者：
DuBose, T
影响因子：
8.8
作者：
Kramer, L;Bauer, E;Gangl, A
通讯作者：
Gangl, A
影响因子：
8.8
作者：
Morgera, Stanislao;Schneider, Michael;Neumayer, Hans-Hellmut
通讯作者：
Neumayer, Hans-Hellmut
影响因子：
8.8
作者：
Gattas, David J.;Rajbhandari, Dorrilyn;Bellomo, Rinaldo
通讯作者：
Bellomo, Rinaldo