Computer simulation of the mechanical stimulation of the saccular membrane of bullfrog
Computer simulation of the mechanical stimulation of the saccular membrane of bullfrog
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DOI：
10.1016/s0378-5955(00)00034-4
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发表时间：
2000-05-01
期刊：
影响因子：
2.8
通讯作者：
Kondrachuk, AV
中科院分区：
文献类型：
--
作者：
Kondrachuk, AV
实验的三维计算机模拟(Benser M.E.，Issa N.P.，Hudspeth A.J.，1993)。听见。文献68,243-252)，用有限元方法对去耳后牛蛙球囊膜表面的机械刺激进行了研究。计算的膜位移分布与实验数据的比较表明，球状膜的凝胶层是不均匀的。与黄斑表面接壤的下层较薄(6-10微米)，其杨氏模数比凝胶膜上部的杨氏模数小20倍(分别为2.5×10~(2)N/m~(2)和6.6×10~(3)N/m~(2))。这一结果和实验修改的可能后果正在讨论中。基于模拟结果的估计支持这样的结论，即发束硬度可能主导耳石膜剪切的弹性电抗(Benser等人，1993)。(C)2000 Elsevier Science B.V.保留所有权利。
A three-dimensional computer simulation of the experiment (Benser M.E., Issa N.P., Hudspeth A.J., 1993. Hear. Res. 68, 243-252), devoted to the mechanical stimulation of the surface of saccular membrane of bullfrog with the otoconial mass removed was carried out by finite-element method. Comparison of the calculated distribution of the membrane displacements with the experimental data indicates that the gel layer of the saccular membrane is inhomogeneous. Its lower, thin (6-10 mu m) sublayer bordering the macular surface has the smaller Young's modulus which is 20 times less than the modulus of the upper part of the gel membrane (2.5 x 10(2) N/m(2) and 6.6 x 10(3) N/m(2), respectively). Possible consequences of this result and modification of the experiment are being discussed. The estimates based on the results of simulation support the conclusion that hair bundle stiffness may dominate the elastic reactance to otolithic membrane shear (Benser et al., 1993). (C) 2000 Elsevier Science B.V. All rights reserved.